Beat The Cancer

NCI Cancer Bulletin for February 7, 2012

2012-02-07T15:14:00.000-08:00

February 7, 2012 • Volume 9 / Number 3

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The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer.

News	Read This Issue

Clinical Trials Point to New Options for Advanced Prostate Cancer »
Additional Surgery after Breast-Conserving Surgery Varies Widely »
Comparing Prostate Cancer Treatments Shows Newer Isn't Always Better »
Oral HPV Infections May Help Explain Why Some Head and Neck Cancers are More Common in Men »
Cancer Screening Rates Lag Behind National Target Levels »
HPV Testing with Self-Collected Samples May Be Valid Cervical Cancer Screening Method »
Genetic Studies Uncover Clues to Childhood Brain Cancers »

· Also in the Journals: CDC Advisory Committee Strengthens Recommendation for HPV Vaccination in Males »

Commentary

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Global Health through Collaboration and Leadership by Dr. Nils Daulaire »
A Conversation with Drs. Christopher Kinsinger and Henry Rodriguez about Sharing Proteomics Data »

In Depth

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Studies Highlight Complexities of Treating Advanced Head and Neck Cancer »
Connecting the Dots: Network Analysis Helps Public Health Researchers Get the Big Picture »
Featured Clinical Trial: Cetuximab and Radiotherapy for HPV-Associated Oropharynx Cancer »

Updates

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FDA Update »
Notes »

Do you know someone who would enjoy receiving the NCI Cancer Bulletin? To send a copy of the latest issue to a colleague, visit www.cancer.gov/ncicancerbulletin. The NCI Cancer Bulletin will be sent to you biweekly unless you unsubscribe. To unsubscribe, send a blank email to nci-bulletin-signoff-request@list.nih.gov.

NCI Cancer Bulletin for January 24, 2012

2012-01-24T14:15:00.000-08:00

January 24, 2012 • Volume 9 / Number 2

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News	Read This Issue

Featured Article: Genetic Abnormality Predicts Treatment Benefit for Patients with Rare
Brain Tumor »
Ovarian Cancer Patients with BRCA Mutations May Fare Better than Non-Carriers »
Experimental Drug Improves Survival in Previously Treated Metastatic Colorectal Cancer »
Differences in Estrogen Metabolism May Influence Breast Cancer Risk »
Epigenetic Study Suggests Possible Treatment for Retinoblastoma »
Also in the Journals: Before Breast Cancer Surgery, Two Anti-HER2 Drugs May Be
Better than One »

Commentary

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A Conversation with the NCI Women Scientist Advisors »

In Depth

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More than a Game: Super Bowl Initiative Helps Scientists Study the "Normal" Breast »
Staying Alive: New Technique Grows Normal and Cancer Cells Rapidly »
Targeted Therapies Offer Treatment Options for Advanced Kidney Cancer »
Featured Clinical Trial: First-in-Humans Study of New Immunotherapy Agent »

Updates

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FDA Update »
Notes »

NCI Cancer Bulletin for January 10, 2012

2012-01-10T17:59:00.000-08:00

January 10, 2012 • Volume 9 / Number 1

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News	Read This Issue

Featured Article: Bevacizumab May Benefit Some Women with Ovarian Cancer »
Use of Robotics May Not Reduce Side Effects of Prostate Cancer Surgery »
Chemotherapy Associated with Microscopic Changes in the Brain »
Drug Shows Promise against Hard-to-Treat Chronic Lymphocytic Leukemia »

In Depth

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Studies Raise Concerns about Partial-Breast Radiation Therapy »
Featured Clinical Trial: Making Decisions about Cancer Prevention Medications for
Breast Cancer »
Physician Data Query Offers Authoritative Information for Cancer Patients and Professionals »

Updates

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Legislative Update »
Notes »

Seasons Greetings from the NCI Cancer Bulletin

2011-12-20T09:42:00.000-08:00

December 20, 2011

Dear NCI Cancer Bulletin Subscriber,

The editors, writers, and technical staff of the NCI Cancer Bulletin would like to wish each of you a joyous holiday season and a happy and healthy new year.

Next month, we will begin our ninth year of publication. Since launching in 2004, we have published nearly 275 issues and over 3,800 cancer research news stories, all of which can be accessed through our archive/search page.

As in years past, we received helpful comments from readers and invaluable scientific advice from many experts in the field, including those from NCI’s divisions, centers, and offices. This guidance has helped the NCI Cancer Bulletin and its writers and videographers achieve a number of accolades in 2011, including a first place award in the highly competitive National Association of Government Communicators Gold Screen competition.

Of course, the true measure of the newsletter is reflected in the important research news and feature stories that appear in each issue. Many of these stories are included in our "2011 Editors' Picks" list. We chose some articles for their potential impact on clinical practice and others for their value as important but underreported topics.

Thank you again for your interest and support in 2011. Look for our next issue on January 10, 2012. We hope you'll continue to read each issue and encourage others to subscribe.

Warm regards,

The NCI Cancer Bulletin Team

NCI Cancer Bulletin for December 13, 2011

2011-12-13T15:02:00.000-08:00

December 13, 2011 • Volume 8 / Number 24

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News	Read This Issue

Featured Article: Late Effects May Not Warrant Adding Radiation to Chemotherapy for Early-Stage Hodgkin Lymphoma »
Combination Therapy Shows Promise for Treating Advanced Breast Cancer »
Most Common Adult Muscular Dystrophy Linked to Increased Cancer Risk »
Two Drugs that Hit One Target Show Efficacy against Metastastic Breast Cancer »
Prostate Cancer Trials Show No Link between Androgen-Deprivation Therapy and Cardiac
Death »

Commentary

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mHealth Summit Keynote Address by Secretary Kathleen Sebelius »
A Conversation with Dr. Barry Kramer about Cancer Prevention Research at NCI »

In Depth

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Panel Encourages Broader Use of Surveillance in Some Men with Prostate Cancer »
Institute of Medicine Releases Report on Breast Cancer and the Environment »
Cancer Clinical Trials System Restructuring Moves Forward »
Featured Clinical Trial: Comparing Postoperative Radiation Therapies for Brain Metastases »
Cancer News Workshop Helps Latin American and U.S. Journalists Interpret Research Results »

Updates

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Notes »

NCI Cancer Bulletin for November 29, 2011

2011-11-29T14:06:00.000-08:00

November 29, 2011 • Volume 8 / Number 23

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News	Read This Issue

Featured Article: Researchers Uncover New Mechanism of Resistance to Melanoma Drug »
Survey of Oncologists Suggests Lack of Progress in Cancer Pain Management »
Trial Confirms Efficacy of HPV Vaccine, Shows Cross-Protection »
Genetic Study Yields Clues to Neuroendocrine Prostate Cancer »

Commentary

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A Conversation with Dr. Mason Bond on Improving the Treatment of Patients
with Ewing Sarcoma »

In Depth

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Study Raises Concerns about Using Cancer Cell Lines to Test Drug Resistance »
Unexpected Complications: Treating Cancer during Pregnancy »
Interpreting Risk: Direct-to-Consumer Genetic Testing »
Featured Clinical Trial: Novel Combination Chemotherapy for Localized Ewing Sarcoma »

Updates

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FDA Update »
Notes »

NCI Cancer Bulletin for November 15, 2011

2011-11-15T16:35:00.000-08:00

November 15, 2011 • Volume 8 / Number 22

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Commentary

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Guest Commentary by Dr. Rachel Ballard-Barbash: The Emerging Evidence about the Role of Obesity in Cancer »

Features

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Uncovering the Mechanisms Linking Obesity and Cancer Risk »
Searching for Clues to Obesity among the Body's Many Microbes »
Bridging Disciplines to Study Possible Cancer-Obesity Links »
The Right Balance: Helping Cancer Survivors Achieve a Healthy Weight »
Learn More: Additional Information and Resources »

News Highlights

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Protein May Regulate Hormone Sensitivity in Breast Cancer »
Epigenetic Therapy Shows Potential in Advanced Lung Cancer »
Treatment Uses Antibodies and Light to Target Cancer Cells »
Genetic Mutation that Raises Melanoma Risk Identified »

Updates

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FDA Update »
Notes »

NCI Cancer Bulletin for November 1, 2011

2011-11-01T15:56:00.001-07:00

November 1, 2011 • Volume 8 / Number 21

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News	Read This Issue

Featured Article: Organ Transplant Recipients Are at Increased Risk for a Range of Cancers »
Annual Screening with Chest X-Ray Does Not Reduce Lung Cancer Deaths »
Radiation Therapy after Breast-Conserving Surgery Improves Survival »
Targeted Therapy Shows Benefit in Rare Type of Thyroid Cancer »
Study Confirms Letrozole Prevents More Breast Cancer Recurrences than Tamoxifen »
Study Suggests Smaller Melanoma Excision Margins May Be Option for Some Patients »
HPV Vaccine Reduces Anal HPV Infection and Precancerous Lesions »

In Depth

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Study Shows Aspirin Reduces Colorectal Cancer in Those at High Risk »
Tackling the Conundrum of Cachexia in Cancer »
Featured Clinical Trial: Cetuximab and Radiotherapy for HPV-Associated Oropharynx Cancer »

Updates

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CDC Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for October 18, 2011

2011-10-18T14:25:00.000-07:00

October 18, 2011 • Volume 8 / Number 20

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News	Read This Issue

Featured Article: Chemotherapy That is Less Toxic to the Heart May Be an Option for Some Women with HER2-Positive Breast Cancer »
Higher-Dose Radiation Does Not Improve Survival in Some Lung Cancer Patients »
BRCA Gene Mutations May Influence Survival, Treatment Response in Ovarian Cancer »
Newer Cancer Drugs May Cause Thyroid to Function Abnormally »
Bacterium Linked to Colorectal Cancer in Two Independent Studies »

In Depth

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Vitamin E Supplements Tied to Increased Risk of Prostate Cancer »
After DES: Tracking the Harms of a Prenatal Drug Exposure »
Profiles in Cancer Research: Dr. Samuel Achilefu »
Featured Clinical Trial: Bortezomib and Chemotherapy for Systemic Light-Chain Amyloidosis »
Cancer Center Profile: Purdue University Center for Cancer Research »

Updates

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AHRQ Update »
Notes »

NCI Cancer Bulletin for October 18, 2011

2011-10-18T14:12:00.001-07:00

October 18, 2011 • Volume 8 / Number 20

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News	Read This Issue

Featured Article: Chemotherapy That is Less Toxic to the Heart May Be an Option for Some Women with HER2-Positive Breast Cancer »
Higher-Dose Radiation Does Not Improve Survival in Some Lung Cancer Patients »
BRCA Gene Mutations May Influence Survival, Treatment Response in Ovarian Cancer »
Newer Cancer Drugs May Cause Thyroid to Function Abnormally »
Bacterium Linked to Colorectal Cancer in Two Independent Studies »

In Depth

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Vitamin E Supplements Tied to Increased Risk of Prostate Cancer »
After DES: Tracking the Harms of a Prenatal Drug Exposure »
Profiles in Cancer Research: Dr. Samuel Achilefu »
Featured Clinical Trial: Bortezomib and Chemotherapy for Systemic Light-Chain Amyloidosis »
Cancer Center Profile: Purdue University Center for Cancer Research »

Updates

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AHRQ Update »
Notes »

NCI Cancer Bulletin for October 4, 2011

2011-10-04T15:41:00.000-07:00

October 4, 2011 • Volume 8 / Number 19

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News	Read This Issue

Featured Article: Combination Therapy May Help Some Patients with Advanced Breast Cancer »
Rising Oropharyngeal Cancer Rates Linked to HPV Infection »
Hospitalization Following Prostate Biopsy Common in Older Men »
Study Examines Sex Differences in Screening Colonoscopy Findings »
Delivering Chemotherapy to the Liver May Benefit Patients with Metastatic Melanoma »
Smoking Cessation Drug Proves Effective in Single-Center Trial »
Also in the Journals: Zoledronic Acid May Benefit Postmenopausal Women with Breast Cancer »

Commentary

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NCI's Office of Advocacy Relations: Bringing Advocacy and Research Together »
A Conversation with Dr. Jane Perlmutter about the Role of Advocates in Cancer Research »

In Depth

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Workshop Examines Causes, Potential Remedies for Drug Shortages »
Changing Face of Cancer in HIV-Positive Patients Requires New Approaches to Clinical Trials »
Featured Clinical Trial: Testing Adjuvant Ipilimumab in Advanced Melanoma »
NCI Director's Consumer Liaison Group Focuses on Improving Clinical Trials »

Updates

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FDA Update »
NIH Update »
Legislative Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for September 20, 2011

2011-09-20T13:09:00.000-07:00

September 20, 2011 • Volume 8 / Number 18

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News	Read This Issue

Featured Article: HPV Vaccine Study in Costa Rica Yields Insights on Cancer Prevention »
For Young Women, Breast Conserving Surgery May Be Acceptable Alternative to Mastectomy »
Fluorescent Probe Helps Surgeons Find Ovarian Cancer Cells »
Nurse Practitioners, Physician Assistants Could Alleviate Projected Oncology Workforce
Shortage »
Study Suggests How the BRCA1 Protein May Help Suppress Tumors »
Bacterium Associated with Stomach Cancer Directly Damages DNA »

Commentary

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A Conversation with Dr. Ted Trimble on NCI's Center for Global Health »

In Depth

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In Breast Cancer, Moving Toward More Personalized Hormone Therapies »
Unpublished Phase III Cancer Trials: Eliminating the Negative? »
Featured Clinical Trial: Studying the Natural Course of Precursor Conditions to Multiple Myeloma »
Researchers Discuss State-of-the Science on Myelodysplastic Syndromes »

Updates

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FDA Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for September 6, 2011

2011-09-06T15:04:00.000-07:00

September 6, 2011 • Volume 8 / Number 17

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News	Read This Issue

Featured Article: FDA Approves New Drugs to Treat Skin, Blood, and Lung Cancers »
Negative Colonoscopy Associated with Low Colorectal Cancer Risk »
Smokers at Greater Risk of Bladder Cancer than Previously Estimated »
Hereditary Mutations in BAP1 Gene Raise Risk of Mesothelioma »
Use of Radioactive Iodine to Treat Thyroid Cancer on the Rise »
Colorectal Cancer Genomes Sequenced »

Commentary

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Inside NCI: A Conversation with Dr. Norm Coleman about Radiation Research »

In Depth

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Clinical Trial Shows Potential Benefit of HPV Vaccine for Anal Cancer »
Targeting the Accomplices: Homing in on Immune Cells that Aid Tumors »
The Art of Medicine: Using Narrative and the Humanities in Medical Training »
Featured Clinical Trial: Sequencing Treatment with a PARP Inhibitor and Chemotherapy »

Updates

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NIH Update »
Notes »

NCI Cancer Bulletin: Top Feature Stories Since January

2011-08-23T10:35:00.000-07:00

August 23, 2011

Dear NCI Cancer Bulletin Subscribers,

The editors, writers, advisors, and technical staff of the NCI Cancer Bulletin would like to thank you for your continued interest in our newsletter. As you may know, we will not publish an issue today due to our summer production break, but we will resume biweekly publication on September 6.

In the meantime, we would like to share some of our favorite and most popular feature stories published in the NCI Cancer Bulletin so far this year:

§ Preserving Fertility While Battling Cancer (January 11)

§ Coming Home to Roost: The Self-Seeding Hypothesis of Tumor Growth (February 8)

§ The Epithelial-Mesenchymal Transition in Cancer: A Potentially Fatal Transformation? (March 8)

§ Ovarian Cancer Study Raises Questions about Developing Markers for Early Detection (March 8)

§ Fertility Still Possible for Many Male Cancer Survivors, Study Finds (March 22)

§ For People with Rare Skin Cancer Syndrome, Drug Brings Relief and Hope (April 5)

§ Debunking Cancer Myths, One Phone Call at a Time (April 19)

§ Use and Acceptance of HPV Vaccine Still a Work in Progress (May 3)

§ Combining Targeted Cancer Therapies: Much Promise, Many Hurdles (May 17)

§ Lenalidomide and Radiation for Children with Brain Cancers (May 17)

§ Despite Early Skepticism, HPV Vaccines Prove Effective (May 31)

§ New Therapies Offer Much-Needed Options for Patients with Melanoma (June 14)

§ Imaging Boot Camp for Cancer Researchers (June 28)

§ AYAs Are Not Alone: Confronting Psychosocial Challenges of Cancer (July 26)

In addition to these features, we have produced a number of videos over the past year. You can access these videos through our YouTube channel.

Thank you again for your interest and support. We hope you'll continue to read each issue and encourage others to subscribe.

We also appreciate your story ideas and feedback. Send your suggestions and comments to us by e-mail at ncicancerbulletin@mail.nih.gov.

Best regards,

The NCI Cancer Bulletin Team

To unsubscribe, please send an email to nci-bulletin-signoff-request@list.nih.gov .

NCI Cancer Bulletin for August 9, 2011

2011-08-09T14:54:00.000-07:00

August 9, 2011 • Volume 8 / Number 16

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News	Read This Issue

Featured Article: Genome Region Tied to Risk of Second Cancers after Radiation Therapy »
Mobile Phone Use Does Not Raise Cancer Risk in Children and Adolescents»
Computer System for Reading Mammograms Does Not Appear to Improve Cancer Detection »
Higher Breast Density Linked to Increased Cancer Risk and Aggressive Tumors »
Genetic Study Provides Clues to Non-Hodgkin Lymphoma »
Studies Reveal the Genetic Complexity of Head and Neck Squamous Cell Cancers »
Also in the Journals: Key Genetic Mutations Found in One Type of Brain Cancer »

In Depth

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Tracking the Rise of Robotic Surgery for Prostate Cancer »
New Guidance for Personalized Breast Cancer Screening »
Featured Clinical Trial: Comparing Targeted Lung Cancer Therapies Based on KRAS Mutation Status »
Translational Science: From Molecular Information to Cancer Medicine »

Updates

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Cancer.gov Update »
Notes »

NCI Cancer Bulletin for July 26, 2011

2011-07-26T19:22:00.001-07:00

July 26, 2011 • Volume 8 / Number 15

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Commentary

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Guest Commentary: Toward a New Understanding of Cancers in Adolescents and Young
Adults »
Cancer Research Now: Adolescent and Young Adult Cancers »

Features

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Uncovering the Biology of Cancers in Adolescents and Young Adults »
Clinical Trials Offer a Path to Better Care for AYAs with Cancer »
For Many Young Cancer Survivors, Late Effects Pose Lasting Problems »
AYAs Are Not Alone: Confronting Psychosocial Challenges of Cancer »
A Conversation with Matthew Zachary: The Young Adult Cancer Movement »

Highlights

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Breast Cancer Cells Found by Immunochemistry in Sentinel Nodes Not Associated with
Survival »
Radiation Plus Short-Term Hormone Therapy Improves Survival of Men with Early-Stage Prostate Cancer »
In Hodgkin Lymphoma Study, Side Effects Distinguish Treatments »

Updates

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FDA Update »
Notes »

NCI Cancer Bulletin for July 12, 2011

2011-07-12T14:22:00.001-07:00

July 12, 2011 • Volume 8 / Number 14

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The latest issue of the NCI Cancer Bulletin is now available at 071211/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer.

News	Read This Issue

Featured Article: U.S. Colorectal Cancer Death Rates Continue to Drop, But Not Equally »
EGFR-Targeted Drug Effective for Some Lung Cancer Patients»
Clinically Relevant Family Histories of Cancer Change Over Time »
Lung Tumor Study Reveals Variability of CT Scans »
Blocking Cdk1 Protein May Sensitize More Tumors to PARP Inhibitors »
Gene Mutations Linked to Altered Telomeres in Cancer Cells »

Commentary

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NCI Cancer Disparities Research: Sharing Ideas, Forging Partnerships »

In Depth

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Whole-Genome Sequencing for Cancer Enters the Clinic »
Featured Clinical Trial: Preventing Smoldering Multiple Myeloma from Progressing »
Inspired by Science: Cancer Research Internships for Minority Students »

Updates

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FDA Update »
CMS Update »
Legislative Update »
Notes »

NCI Cancer Bulletin for June 28, 2011

2011-06-28T14:58:00.000-07:00

June 28, 2011 • Volume 8 / Number 13

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News	Read This Issue

Featured Article: New Graphic Tobacco Warning Labels Backed by Research »
Common Gene Mutation Found in Hairy Cell Leukemia »
New Cancer Vaccine Shows Promise against Tumors in Mice »
Researchers Scrutinize Genetic Variants Linked to Melanoma »
Barrett Esophagus May Progress to Cancer Less Often than Thought »

Commentary

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A Conversation with Dr. Martha Linet on Cell Phone Use and Cancer Risk »

In Depth

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Imaging Boot Camp for Cancer Researchers »
Featured Clinical Trial: Adding Targeted Therapy to Treatment for Esophageal Cancer »

Updates

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FDA Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for June 14, 2011

2011-06-14T14:14:00.001-07:00

June 14, 2011 • Volume 8 / Number 12

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News	Read This Issue

Featured Article: New Therapies Offer Much-Needed Options for Patients with Melanoma »
Ovarian Cancer Screening Method Fails to Reduce Deaths from the Disease »
Longer Imatinib Treatment for GIST Improves Survival »
High-Dose Methotrexate Extends Event-Free Survival for Children with Leukemia »
Combining Chemotherapy with Bevacizumab Improves Outcomes for Ovarian Cancer Patients »
Experimental Drug Shrinks Tumors in Rare Sarcoma »
International Study Tests Additional Radiation Therapy for Breast Cancer »
Patient Navigation Leads to Fewer Missed Oncology Appointments »

In Depth

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Exemestane Substantially Reduces Breast Cancer Risk »
Perfect Match: Unraveling the Origin of XMRV »
Featured Clinical Trial: Combining Second-Line Targeted Therapies for Advanced
Kidney Cancer »
Cancer Advocates at ASCO: Connecting for a Cause »

Updates

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FDA Update »
Notes »

NCI Cancer Bulletin for May 31, 2011

2011-05-31T17:56:00.001-07:00

May 31, 2011 • Volume 8 / Number 11

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News	Read This Issue

Featured Article: Study Questions Benefit of Surgery versus Watchful Waiting in Some with Prostate Cancer »
Cabozantinib Shrinks Tumors and Bone Metastases in Prostate and Other Cancers »
Also in the Journals: Cabozantinib May Shrink Some Rare Thyroid Tumors »
End-of-Life Care for Lung Cancer Patients Differs in U.S. and Ontario »
Researchers Identify New Way Tumor Cells May Adapt to Stressful Conditions »

In Depth

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HPV and Pap Co-Testing Safely Extend Cervical Cancer Screening Intervals »
Despite Skepticism, HPV Vaccine Proves Effective »
Featured Clinical Trial: Metformin to Treat Early-Stage Breast Cancer »
Scientific Meetings through the Lens of Twitter »

Updates

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FDA Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for May 17, 2011

2011-05-17T15:46:00.000-07:00

May 17, 2011 • Volume 8 / Number 10

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News	Read This Issue

Featured Article: Chemotherapy Regimen Extends Survival in Advanced Pancreatic Cancer Patients »
Study Finds Colonoscopy Screening Overused in Medicare Beneficiaries »
Prostate Cancer Study Provides More Data on Surgery versus Watchful Waiting »
Breast Cancers Arising between Mammograms Have Aggressive Features »
Patient Reports of Family Cancer History Are Often Inaccurate »

In Depth

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In Rare Skin Cancer, Virus Emerges as Target and Tool »
Straight from the Source: Electronic Patient-Reported Outcomes »
Combining Targeted Cancer Therapies: Much Promise, Many Hurdles »
Featured Clinical Trial: Lenalidomide and Radiation for Children with Brain Cancers »

Updates

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FDA Update »
Legislative Update »
Notes »

NCI Cancer Bulletin for May 3, 2011

2011-05-03T17:58:00.001-07:00

May 3, 2011 • Volume 8 / Number 9

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News	Read This Issue

Featured Article: FDA Approves Abiraterone for Advanced Prostate Cancer »
Tool Weighs Benefits, Risks of Raloxifene or Tamoxifen to Prevent Breast Cancer »
Intensity-Modulated Radiation Therapy Use for Breast Cancer Influenced by Reimbursement »
Whole-Genome Sequencing Improves Cancer Diagnoses »
Researchers Identify Proteins that Help Hepatitis C Virus Enter Liver Cells »

Commentary

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A Conversation with Drs. Maureen Hatch and Kiyohiko Mabuchi on the 25th Anniversary of the Chernobyl Nuclear Disaster »

In Depth

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Chernobyl Tissue Bank Provides a Unique Resource to Researchers »
Use and Acceptance of HPV Vaccine Still a Work in Progress »
Design Dilemma: The Debate over Using Placebos in Cancer Clinical Trials »
Featured Clinical Trial: Testing Dose-Dense Paclitaxel for Ovarian and Related Cancers »

Updates

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FDA Update »
Legislative Update »
Notes »

NCI Cancer Bulletin for April 19, 2011

2011-04-19T21:05:00.000-07:00

April 19, 2011 • Volume 8 / Number 8

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News	Read This Issue

Featured Article: Active Surveillance May Be Preferred Option in Some Men with
Prostate Cancer »
Cancer Burden among People Infected with HIV Changing in U.S. »
Genetic Study Yields New Clues to Melanoma »
Signaling Molecule Selectively Kills Breast Cancer Cells »

Commentary

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Inside NCI: A Conversation with Dr. Lauren Wood »

In Depth

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Investigating Nature's Mysteries for Drug Development »
Debunking Cancer Myths, One Phone Call at a Time »
Featured Clinical Trial: Cediranib to Treat Alveolar Soft Part Sarcoma »

Updates

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FDA Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for April 5, 2011

2011-04-05T16:41:00.000-07:00

April 5, 2011 • Volume 8 / Number 7

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News	Read This Issue

Featured Article: Crossing Disciplines to Explore Questions about Cancer »
Latest Surveillance Data Show Cancer Cases and Deaths Continue to Decline »
Patients Taking Imatinib for CML Have Similar Risk of Death as General Population »
Risk of Second Cancer Following Radiation Therapy Is Small »
Immunotherapy Targets Pancreatic Tumors from the Outside »
Breast Cancer Genomes Sequenced to Study Drug Response »
Combination of Two Targeted Cancer Drugs Appears Safe in Early Testing »
Test May Detect Mesothelioma at the Earliest Stages »

In Depth

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Menopausal Estrogen Therapy Benefits and Risks Vary by Age, WHI Analysis Suggests »
For People with Rare Skin Cancer Syndrome, Drug Brings Relief and Hope »
Genome Study of Multiple Myeloma Opens New Avenues for Research »
Featured Clinical Trial: Inhibiting Tumor Angiogenesis in Metastatic Hormone-Refractory Prostate Cancer »

Updates

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FDA Update »
CMS Update »
Legislative Update »
Notes »

NCI Cancer Bulletin for March 22, 2011

2011-03-22T18:58:00.000-07:00

March 22, 2011 • Volume 8 / Number 6

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News	Read This Issue

Featured Article: Fertility Still Possible for Many Male Cancer Survivors, Study Finds »
U.S. Cancer Survivors Increase to Nearly 12 Million »
Thyroid Cancer Risk Persists in People Exposed to I-131 Radiation as Children »
Incidence Rate of Second Cancer in the Opposite Breast Has Declined in U.S. »
Eribulin Improves Survival of Women with Metastatic Breast Cancer »
Experimental Strategy May Overcome Resistance to Breast Cancer Drug »

Commentary

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Devastation and Hope: An NCI Scientist's First-Hand Account of Japan's Resilience »

In Depth

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Colorectal Cancer Test Targets Cancer Stem Cells in Blood »
Miniaturized Device Puts Nanotechnology to Work in Diagnosing Cancer »
Featured Clinical Trial: Novel Combination Chemotherapy for Localized Ewing Sarcoma »

Updates

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FDA Update »
Notes »

NCI Cancer Bulletin for March 8, 2011

2011-03-08T19:10:00.000-08:00

March 8, 2011 • Volume 8 / Number 5

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News	Read This Issue

Featured Article: Ovarian Cancer Study Raises Questions about Developing Markers for Early Detection »
Surgical Biopsy Is Overused for Evaluating Suspicious Breast Imaging Findings »
Adding Radiation to Chemotherapy Improves Outcomes in Early-Stage Hodgkin Lymphoma »
Trastuzumab after Chemotherapy Is Effective in HER2-Positive Breast Cancer »
Denosumab Reduces Risk of Bone Side Effects in Advanced Prostate Cancer »
High Rates of Human Papillomavirus Infection Found in Men »

Commentary

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Reenergizing the Agenda for Cancer Communication »

In Depth

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PSA Velocity Does Not Improve Prostate Cancer Detection »
The Epithelial-Mesenchymal Transition in Cancer: A Potentially Fatal Transformation? »
Featured Clinical Trial: Optimizing Adjuvant Therapy for Resected Pancreatic Cancer »
Radically Reducing Radiation Exposure during Routine Medical Imaging »

Updates

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Legislative Update »
Notes »

NCI Cancer Bulletin - February 22, 2011

2011-02-22T18:42:00.000-08:00

February 22, 2011 • Volume 8 / Number 4

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News	Read This Issue

Featured Article: Some Women May Not Need More Extensive Lymph Node Surgery for Breast Cancer »
Dutasteride May Slow Growth of Early-Stage Prostate Cancer »
Bisphosphonate Use May Reduce Colorectal Cancer Risk »
Common Genetic Deletion Found in Brain Cancers »
More DNA Rearrangements Found in Prostate Cancers »
Certain Physicians Are More Likely to Refer Patients to Clinical Trials »

In Depth

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Targeted Therapies May Be Effective Against Rare Pancreatic Cancer »
Profiles in Cancer Research: Dr. Robin Yabroff »
Featured Clinical Trial: Treating Multiply Relapsed or Refractory Hairy Cell Leukemia »

Updates

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HHS Update »
FDA Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for February 8, 2011

2011-02-08T19:18:00.000-08:00

February 8, 2011 • Volume 8 / Number 3

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Featured Article: When Combined with Chemo, Bevacizumab Is Associated with Increased Risk of Death »
Starting Hormone Therapy at Menopause Increases Breast Cancer Risk »
Vaccine Reduces HPV Infections in Young Men »
Adoptive Cell Transfer Targets New Cancer Antigen for Immunotherapy »
Mouse Studies Point to Prognostic Test for Prostate Cancer »
Protein May Help Predict Cancer Recurrence and Metastasis »

In Depth

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Coming Home to Roost: The Self-Seeding Hypothesis of Tumor Growth »
Featured Clinical Trial: Study of a Statin to Prevent Polyps after Colon Cancer Resection »
Translating Clinical Care for Callers to NCI's Cancer Information Service »

Updates

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FDA Update »
Notes »

NCI Cancer Bulletin for January 25, 2011

2011-01-25T16:28:00.001-08:00

January 25, 2011 • Volume 8 / Number 2

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Featured Article: Genetic Study Reveals Clues to Pancreatic Neuroendocrine Tumors »
Trial Suggests New Treatment Option for Gastrointestinal Stromal Tumors »
Gene Test for Risk of Colorectal Cancer Recurrence Validated »
Newly Discovered Mutations May Help Drive Common Kidney Cancer »
Interferon-gamma Promotes UV-Induced Melanoma in a Mouse Model »

Commentary

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A Conversation with Dr. Angela Mariotto and Dr. Martin Brown on the Rising Costs of Cancer Care »

In Depth

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Can Aspirin Reduce Cancer Risk and Mortality? »
Seeking Better Treatments for Brain Tumors in Children »
Featured Clinical Trial: Dose-Adjusted Chemotherapy for Untreated c-MYC-Positive Lymphomas »
NCI Director Provides Update on New Programs and Initiatives »

Updates

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FDA Update »
Notes »

NCI Cancer Bulletin for January 11, 2011

2011-01-11T16:55:00.001-08:00

January 11, 2011 • Volume 8 / Number 1

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Featured Article: Continued Shortage of Chemotherapy Drugs Causing Concern »
Another JAK2 Inhibitor Shows Promise against Myelofibrosis »
Treatment for Ductal Carcinoma In Situ Varies Substantially »
Major Gene Mutation Identified in Lymphoma Tumors »

Commentary

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Inside NCI: A Conversation with Dr. Barry Kramer about Cancer Screening »

In Depth

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Preserving Fertility While Battling Cancer »
Featured Clinical Trial: Comparing First-Line Therapies for Mucinous Ovarian or Fallopian Tube Cancer »
The Kimmel Cancer Center at Thomas Jefferson University »

Updates

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Notes »

Seasons Greetings

2010-12-28T13:45:00.000-08:00

December 28, 2010

Dear NCI Cancer Bulletin Subscriber,

The editors, writers, and technical staff of the NCI Cancer Bulletin would like to wish each of you a safe and joyous holiday season and a happy and healthy new year.

Next month, we will begin our eighth year of publication. Since launching in 2004, we have published nearly 250 issues and well over 3,500 cancer research news stories, all of which can be accessed through our archive/search page.

Last year in particular brought a host of important news and feature stories. Many of these are included in our "2010 Editors' Picks" list. We chose these stories not only for their potential impact on clinical practice, but also for their value as important but underreported topics.

Finally, here is a sneak peek at our 2010 reader satisfaction survey results, which will also be posted in our first issue of 2011. Thanks to all who participated and sent in suggestions and comments. The overall results mirror our 2007 survey and, while there are obvious limitations with any voluntary survey, we believe the data and suggestions will help inform our future plans for the newsletter as we strive to meet reader needs and expectations.

Thank you again for your interest and support in 2010. We hope you'll continue to read each issue and encourage others to subscribe.

Best regards,

The NCI Cancer Bulletin Team

NCI Cancer Bulletin for December 14, 2010

2010-12-14T15:06:00.000-08:00

December 14, 2010 • Volume 7 / Number 24

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New Surgeon General's Report Outlines How Tobacco Smoke Causes Disease »
Study Estimates More than 600,000 Deaths Worldwide Caused by Secondhand Smoke »
Zoledronic Acid Does Not Improve Disease-Free Survival in Breast Cancer »
Regular Sunscreen Use May Reduce Invasive Melanoma Risk »
Hormone Therapy for Low-Risk Prostate Cancer Declines When Medicare Reimbursements Are Reduced »
Study Shows Strong Link between Obesity and Mortality »
New Subtype of Acute Myeloid Leukemia Identified »
Screening Compliance, Stage of Cancers Detected Vary by Demographic »

Commentary

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A Conversation with Dr. James Doroshow about NCI's Clinical Trials Cooperative Group Program »

In Depth

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Trial Suggests New Treatment Option for Hodgkin Lymphoma »
Featured Clinical Trial: Targeting Tumor Metabolism in Papillary Kidney Cancers »
Statistical Strength in Numbers: International Clinical Trials for Rare Cancers »

Updates

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FDA Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for November 30, 2010

2010-11-30T18:21:00.000-08:00

November 30, 2010 • Volume 7 / Number 23

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Commentary

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Where Science Meets Culture: The Art of Health Diplomacy »

News	Read This Issue

In Bangladesh, Developing Models for Cancer Care »
The Cancer Expert Corps: An Idea for Building Human Capital »
Cancer Communicators in Latin America Get Support at NCI Workshop »
Considering Culture When Providing Cancer Care »
NCI’s International Cancer Research Resources »

Highlights

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Prostate Cancer Hormone Treatments May Raise Risk of Colorectal Cancer »
Strategy to Screen for Lynch Syndrome May Save Lives and Be Cost Effective »
Anemia Drug May Interfere with Trastuzumab’s Anticancer Effects »
Possible Causes of Resistance to Melanoma Drug Reported »
Radiation Treatment for Head and Neck Cancer May Produce Hearing Loss »

Updates

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FDA Update »
CMS Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for November 16, 2010

2010-11-16T16:14:00.000-08:00

November 16, 2010 • Volume 7 / Number 22

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Featured Article: HHS Releases New Tobacco Control Strategy for the Nation »
Mutated Gene Linked to Poor Survival in Acute Myeloid Leukemia »
Novel Drug Effectively Shrinks Tumors in Hodgkin Lymphoma »
Indefinite Imatinib Therapy May Not Be Necessary for Some CML Patients »
Lasofoxifene Is Potential New Option for Breast Cancer Risk Reduction »
Some Cells in Stroma May Block Immune System's Antitumor Effects »

In Depth

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Low-Dose CT Shows Clear Mortality Benefit for Lung Cancer Screening in Heavy Smokers »
Uncertain Road for Potential Ewing Sarcoma Therapy »
Featured Clinical Trial: Combination Therapy for Advanced Kaposi Sarcoma »
Families and Scientists Gather to Discuss Research and Treatment for Li-Fraumeni Syndrome »

Updates

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Legislative Update »
Cancer.gov Update »
Notes »

Breaking News from the NCI Cancer Bulletin

2010-11-04T10:39:00.000-07:00

November 4, 2010

Lung Cancer Trial Results Show Mortality Benefit with Low-Dose CT

NCI has released initial results from the National Lung Screening Trial (NLST), a randomized national trial involving more than 53,000 current and former heavy smokers ages 55 to 74. The trial compared the effects of two lung cancer screening procedures—low-dose helical computed tomography (CT) and standard chest X-ray—on lung cancer mortality and found 20 percent fewer lung cancer deaths among trial participants screened with low-dose helical CT. Read more >>

NCI Cancer Bulletin for November 2, 2010

2010-11-02T16:07:00.000-07:00

November 2, 2010 • Volume 7 / Number 21

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Crizotinib Continues to Show Promise for Some Lung Tumors, Faces Challenge of Drug Resistance »
Pancreatic Cancers May Develop Slowly Over Many Years »
Cetuximab May Benefit Some Patients with KRAS Gene Mutations »
Protein Found on Tumor Blood Vessels Might Be Cancer Target »
More Evidence Suggests Aspirin May Prevent Colorectal Cancer »

In Depth

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Engineering Progress against a Rare Cancer »
Featured Clinical Trial: Targeted Antibody Therapy for Metastatic Adrenocortical Carcinoma »
Recognition of Animal Welfare in Biomedical Science Takes Center Stage »

Updates

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FDA Update »
Notes »

NCI Cancer Bulletin for October 19, 2010

2010-10-19T16:41:00.000-07:00

October 19, 2010 • Volume 7 / Number 20

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Featured Article: Cancer Screening Continues Even after Patients Are Diagnosed with Terminal Cancer »
Abiraterone Improves Survival in Metastatic Prostate Cancer »
Similar Early-phase Trials Prohibit Different Drugs, Undermining Outcomes »
Surgical Procedure Reduces Disability and Pain Caused by Spine Fractures in Cancer Patients »

Commentary

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Guest Commentary: Bringing Science to the Market »

In Depth

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Hormone Therapy Linked to Modest Increase in Breast Cancer Deaths »
Testing a "Smarter" Biopsy for Prostate Cancer »
Partners in Crime: Using Synthetic Lethality to Identify New Cancer Targets »
Featured Clinical Trial: Eliminating Hairy Cell Leukemia Minimal Residual Disease »

Updates

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FDA Update »
HHS Update »
Notes »

NCI Cancer Bulletin Survey Reminder

2010-10-06T14:01:00.000-07:00

October 6, 2010

Dear Reader,

Time is running out for your participation in the NCI Cancer Bulletin reader survey. Subscribers like you are a key source of information on how to improve the newsletter and help ensure that the needs of readers are met.

If you have already completed the survey, thank you and please disregard the rest of this message.

If you have not yet completed the survey, we would like to invite you one last time to click here to complete the survey no later than Tuesday, October 12, 2010. The survey should take you about 5–10 minutes to complete and your responses will be anonymous.

Thank you in advance for your participation. We welcome your input and look forward to sharing the results of the survey in an upcoming issue of the NCI Cancer Bulletin.

Sincerely,

The NCI Cancer Bulletin Staff

NCI Cancer Bulletin for October 5, 2010

2010-10-05T16:40:00.001-07:00

October 5, 2010 • Volume 7 / Number 19

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Featured Article: Experts Urge Further Research on Nicotine Reduction to Decrease Tobacco Addiction »
Less-invasive Lymph Node Surgery Safe for Women with Breast Cancer »
HPV Screen-and-Treat Methods Prevent Cervical Cancer Precursors in Low-resource Settings »
Black Patients with Advanced Cancer Are More Likely to Receive Unwanted Care at End of Life »
Genetic Study Finds Clue to Gastrointestinal Stromal Tumors »

In Depth

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Studies Provide New Data on Mammography and Breast Cancer Mortality »
Turning the Immune System against a Childhood Cancer »
Featured Clinical Trial: Preventing Chemotherapy-related Hearing Loss in Young Cancer
Patients »
Profiles in Cancer Research: Dr. Pier Paolo Pandolfi »
Physician Assistants Valued for Patient Care and Research Support at NCI »

Updates

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Cancer.gov Update »
Notes »

NCI Cancer Bulletin Survey Reminder

2010-09-28T15:22:00.000-07:00

September 28, 2010

Dear Reader,

The National Cancer Institute (NCI) is gathering feedback on the NCI Cancer Bulletin. Subscribers like you are a key source of information on how to improve the newsletter and help ensure that the needs of readers are met.

We hope you will choose to participate in the survey. If you have already completed the survey, thank you and please disregard the rest of this message.

If you have not yet completed the survey, please click here to complete the survey no later than Tuesday, October 12, 2010.

It will take approximately 10 minutes to complete and your responses will be anonymous.

Thank you in advance for your participation. We welcome your input and look forward to sharing the results of the survey in an upcoming issue of the NCI Cancer Bulletin.

Sincerely,

The NCI Cancer Bulletin Staff

NCI Cancer Bulletin for September 21, 2010

2010-09-21T16:11:00.000-07:00

September 21, 2010 • Volume 7 / Number 18

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Featured Article: Drug Protects Heart in Children Receiving Common Chemotherapy »
Mutations Linked to Two Uncommon Forms of Ovarian Cancer »
Declines in U.S. Smoking Prevalence Stalled »
Men with Low PSA Levels May Not Benefit from Further Prostate Cancer Screening »
Hospitalization Near Death May Diminish Mental Health of Caregivers and Quality of Life for Cancer Patients »

In Depth

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When Ovarian Cancer Returns Years Later »
XMRV Researchers Discuss the State of the Science »
Featured Clinical Trial: Combining Vaccine and Antiandrogen Therapy for Prostate Cancer »
Quitting Smoking? Find Support on Facebook »

Updates

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Cancer.gov Update »
FDA Update »
Notes »

NCI Cancer Bulletin Survey

2010-09-14T12:41:00.000-07:00

September 14, 2010

Dear Reader,

The National Cancer Institute (NCI) has been publishing the NCI Cancer Bulletin since 2004. We regard you, the subscriber, as an important source of information on how to improve the newsletter and help ensure that the needs of readers are met. We would appreciate your participation in a brief survey to gather feedback on the NCI Cancer Bulletin. Your comments are extremely valuable.

Please click here to complete the survey no later than Tuesday, October 12, 2010.

The survey will take approximately 10 minutes to complete, and your responses will be anonymous.

Thank you in advance for your comments. We welcome your input and look forward to sharing the results of the survey in an upcoming issue of the NCI Cancer Bulletin.

Sincerely,

The NCI Cancer Bulletin Staff

NCI Cancer Bulletin for September 7, 2010

2010-09-07T16:23:00.000-07:00

September 7, 2010 • Volume 7 / Number 17

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Featured Article: Targeted Drug for Melanoma Shows Promise in Early Clinical Testing »
For Women with BRCA Mutations, Prophylactic Surgery Reduces Cancer Risk »
Less-intensive Treatment Regimen Effective against Multiple Myeloma »
Lower-dose Treatments for Early-stage Hodgkin Lymphoma Do Not Compromise Results »
Chemotherapy Affects Brain Structure of Breast Cancer Patients »
Consuming High Levels of Red Meat and Fat May Increase Liver Cancer Risk »
Cancer Patients Leaving Hospice Early Boost Medicare Expenditures »

Commentary

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Inside NCI: A Conversation with Dr. Crystal Mackall about Pediatric Oncology »

In Depth

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Palliative Care Improves Survival, Quality of Life in Advanced Lung Cancer »
Autophagy: The Strange Dining Habits of Cancer Cells »
Featured Clinical Trial: Comparing Post-transplant Therapies for Multiple Myeloma Patients »

Updates

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Notes »

NCI Cancer Bulletin: Top 10 Feature Stories Since January

2010-08-24T11:01:00.000-07:00

August 24, 2010

Dear NCI Cancer Bulletin Subscriber,

The editors, writers, and technical staff of the NCI Cancer Bulletin would like to thank each of you for your continued interest in our newsletter. We will not publish an issue today due to our summer production break, but we will resume biweekly publication on September 7.

In the meantime, we have compiled a list below of the 10 most popular feature-length stories published so far this year, according to reader page views:

FDA Approves First Therapeutic Cancer Vaccine (May 4)
Physicians Urged to Consider Active Surveillance in Prostate Cancer (Jan. 12)
Experimental Drug Benefits Patients with Advanced Prostate Cancer (Mar. 9)
Chemotherapy-induced Peripheral Neuropathy (Feb. 23)
The Downside of Diagnostic Imaging (Jan. 26)
Melanoma Drugs Have Unintended Effects in Some Tumors (Feb. 9)
New Cancer Drugs Bring New Side Effects, and Nurses Respond (Jan. 12)
Trials Point to Potential Advances in Lung Cancer Treatment (Jan. 26)
Personalizing Biomarkers for Cancer (Feb. 23)
I-SPY2: Breast Cancer Trial Aims to Speed Drugs to the Clinic (Mar. 23)

We are especially proud of our ability to bring you stories like these through RSS and Twitter feeds, as well as to present our content via a variety of platforms like YouTube and Facebook. In addition, for those who may prefer to read selected articles in Spanish, we have a Spanish-language version of the newsletter.

Thank you again for your interest and support. We hope you’ll continue to read each issue and encourage others to subscribe.

Best regards,

The NCI Cancer Bulletin Team

NCI Cancer Bulletin for August 10, 2010

2010-08-10T14:21:00.000-07:00

August 10, 2010 • Volume 7 / Number 16

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Featured Article: Protein Helps Predict Cancer Therapy-induced Heart Damage »
Bone Drugs Do Not Appear to Increase Esophageal or Gastric Cancer Risk »
Immune Cells' Anticancer Abilities May Be Hampered by High Lipid Levels »
microRNA May Regulate Growth of Tumor Blood Vessels »
Many U.S. and Canadian Oncologists Unprepared to Use Cost-effectiveness Data in Practice »

In Depth

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A Cancer Treatment That Sticks Around »
NCI's Cancer Information Service: Providing Information and Assistance Nationwide »
Featured Clinical Trial: Cediranib to Treat Alveolar Soft Part Sarcoma »
The Comprehensive Cancer Center of Wake Forest University »

Updates

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Legislative Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for July 27, 2010

2010-07-27T14:47:00.000-07:00

July 27, 2010 • Volume 7 / Number 15

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Featured Article: FDA Advisory Committee Recommends against Bevacizumab for Metastatic Breast Cancer »
PSA Screening Leads to Aggressive Treatment, Even in Older Men at Low Risk »
Chemotherapy Regimen Benefits Men with Metastatic Penile Cancer »
Hormone Therapy Increases Breast Cancer Risk for Women with Dense Breasts »
Brain Cancer Incidence Trends Do Not Support Link to Cell Phones »
Expert Panel Reports on Knowledge Gaps for 20 Suspected Carcinogens »

In Depth

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The Evolving Science of Cancer Stem Cells »
When Brain Cancer Returns, New Test May Aid Decisions about Surgery »
Using e-Health Tools to Improve Quality of Life for Cancer Patients »
Profiles in Cancer Research: Dr. Carol Fabian »
Featured Clinical Trial: Electroacupuncture for Radiation-induced Chronic Dry Mouth »

Updates

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Notes »

NCI Cancer Bulletin for July 13, 2010

2010-07-13T15:05:00.000-07:00

July 13, 2010 • Volume 7 / Number 14

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Featured Article: Harold Varmus Becomes Fourteenth Director of the National Cancer Institute »
Adherence Low among Women Taking Adjuvant Hormone Therapy for Early-stage Breast Cancer »
Drug that Inhibits DNA-repair Enzyme Shrinks Some Breast and Ovarian Tumors »
Colorectal Cancer Screening Rates Rise, Mammography Rates Dip Slightly in the U.S. »
Length of Telomeres Linked to Risk for Some Cancers »
Study Estimates Cancer Cases Due to Radiation Exposure in the Marshall Islands »

In Depth

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Synthetic Biology and Cancer: Exploring the Possibilities »
Can PSA Screening Decrease Prostate Cancer Mortality? »
Featured Clinical Trial: Targeting HER2 in the Treatment of Ductal Carcinoma In Situ »
Cancer Survivors Discover the Power of Blogging »

Updates

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Legislative Update »
NIH Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for June 29, 2010

2010-06-29T14:10:00.000-07:00

June 29, 2010 • Volume 7 / Number 13

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Genome Studies Start to Unravel Prostate Cancer's Complexity »
Gefitinib Improves Outcomes for Metastatic Lung Cancers with EGFR Mutations »
Study Finds Poor Physician Adherence to Cervical Cancer Screening Guidelines »
Targeted Drug Tested in Children with Recurrent Medulloblastoma »
Vitamin D Concentrations in Blood Not Linked to Risk of Less Common Cancers »
Cancer Survivors More Likely Than Peers to Forgo Medical Care Due to Cost »

Commentary

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Guest Director's Update: Cancer Survivorship Research Conference—Recovery and Beyond »

In Depth

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Guidelines Urge Exercise for Cancer Patients, Survivors »
Four Breast Cancer Trials with Clinical Implications »
Featured Clinical Trial: Inhibiting Angiogenesis in Metastatic Castration-resistant Prostate Cancer »

Updates

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FDA Update »
HHS Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for May 18, 2010

2010-05-18T17:23:00.001-07:00

May 18, 2010 • Volume 7 / Number 10

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Commentary

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Director's Update: For Clinical Trials, a Time of Challenge, Change, and Opportunity »
Inside NCI: A Conversation with Dr. Jeff Abrams about Cancer Clinical Trials »

News	Read This Issue

Cancer Trials Accrual Tool Focuses on Solutions »
Insurance Coverage Expanding for Cancer Clinical Trials »
Talking about Trials: Overcoming Bottlenecks in Clinical Communication »
Taking Action to Diversify Clinical Cancer Research »
Overcoming Age Limits in Cancer Clinical Trials »
Additional Clinical Trials Resources »

Highlights

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Study Finds No Overall Increased Brain Tumor Risk from Cell Phones »
Cost of Cancer Care in the United States Doubled in the Past 20 Years »
Liver Cancer Cases in the United States Continued to Rise Through 2006 »
Doctors Urged to Monitor Hypertension in Cancer Patients Treated with Anti-VEGF Therapies »

Updates

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Legislative Update »
Cancer.gov Update »
Notes »

Breaking News from the NCI Cancer Bulletin

2010-05-17T17:18:00.001-07:00

May 17, 2010

President Obama to Appoint Harold Varmus, M.D., to Lead the National Cancer Institute

Today, President Barack Obama announced his intent to appoint Harold Varmus, M.D., to serve as Director of the National Cancer Institute (NCI).

In an e-mail to the NCI staff, Francis Collins, M.D., Ph.D., Director of the National Institutes of Health, said that Varmus "brings unmatched expertise at all levels - not only in cutting edge scientific research, but also as a leader in the development of strategies for improving patient care, in scientific education and training, and in the design of novel public-private partnerships."

NCI Cancer Bulletin for May 4, 2010

2010-05-04T14:17:00.000-07:00

May 4, 2010 • Volume 7 / Number 9

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News	Read This Issue

FDA Approves First Therapeutic Cancer Vaccine »
Breast Tissues May Express Biomarkers Linked to DCIS Recurrence »
Circulating Tumor Cells Detected in Patients with Localized Cancers »
Costs and Use of Diagnostic Imaging Rise among Medicare Patients »

Commentary

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Guest Director's Update: NCCCP—Building a Community-based Research Platform and Enhancing Cancer Care »

In Depth

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Sigmoidoscopy Markedly Reduces Colorectal Cancer Incidence, Mortality »
When Allogeneic Stem Cell Transplants Fail »
Featured Clinical Trial: Vaccine Therapy for Patients with Recurrent Blood Cancers »

Updates

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FDA Update »
Legislative Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for April 20, 2010

2010-04-20T15:58:00.000-07:00

April 20, 2010 • Volume 7 / Number 8

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News	Read This Issue

Long-term Follow-up Confirms Breast Cancer Risk Reduction with Raloxifene »
MicroRNAs Linked to Trastuzumab Resistance, Brain Metastases »
Diabetes Drug Metformin Prevents Lung Tumors in Mice »
Cancer Risk Tools May Need Regular Recalibration »
Profiling Airway Cells May Identify Smokers at Highest Risk of Cancer »
Peptide Helps Chemotherapy Penetrate Deep into Tumors »

Commentary

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Director's Update: An Unexpected Opportunity, a Welcome Honor »
Guest Commentary by Dr. Carolyn Clancy: Focusing the Research Enterprise on the Patient »

In Depth

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Trial Makes Push Toward More Individualized Lung Cancer Therapy »
Genome Study of Aggressive Breast Cancer Yields Clues to Metastasis »
Featured Clinical Trial: Pioglitazone for Oral Premalignant Lesions »
IoM Committee Recommends Overhaul of NCI Clinical Trials Cooperative Group Program »

Updates

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FDA Update »
Legislative Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for April 6, 2010

2010-04-06T15:08:00.000-07:00

April 6, 2010 • Volume 7 / Number 7

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Dutasteride Decreases Prostate Cancer Risk »
Phase III Lung and Pancreatic Cancer Trials Stopped »
Use of Health Care Services May Contribute to Colorectal Cancer Disparities »
Complementary and Alternative Medicine Commonly Used by Pediatric Patients »
Breast Cancer Study Tests Effects of Zoledronic Acid »

Commentary

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Guest Director's Update: Improving the Efficiency of Clinical Trials—Decreasing Activation Times by Fifty Percent »
Guest Commentary by Ambassador Nancy Brinker: Collaborating Globally to Address Breast Cancer in Latin America »
A Conversation with Dr. Robert T. Croyle on Communicating Science »

In Depth

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Scientists Restore DNA Repair in Mice with BRCA1 Gene Mutations »
Focusing on Older Cancer Patients: A Clinical Need and a Research Necessity »
Featured Clinical Trial: New Chemotherapy Drug for Advanced Cervical Cancer »
Cancer Center Profile: Indiana University Melvin and Bren Simon Cancer Center »

Updates

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Legislative Update »
FDA Update »
Notes »

NCI Cancer Bulletin for March 23, 2010

2010-03-23T14:00:00.000-07:00

March 23, 2010 • Volume 7 / Number 6

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News	Read This Issue

I-SPY2: Breast-cancer Trial Aims to Speed Drugs to the Clinic »
Many Older Colorectal Cancer Patients Do Not Receive Adjuvant Chemotherapy »
Drug Slows Progression of Cutaneous T-Cell Lymphoma »
Prognostic Marker for Hodgkin Lymphoma Could Improve Care »
Nanoparticle-based Therapy Triggers RNA Interference in Human Tumors »

Commentary

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Guest Director's Update: Improving Delivery of Quality Cancer Care »
Guest Commentary by Dr. Andrea Barsevick: Fatigue—Is it Normal or Pathological? And How Can We Best Treat It? »
A Conversation with Dr. Ann Berger on Palliative Care at NIH »

In Depth

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Common Genetic Variants Modestly Improve Breast-cancer Risk Models »
Training Providers and Patients to Talk about End-of-Life Care »
Treating the Whole Person in the City of Hope Lung Cancer Study »
Featured Clinical Trial: Vaccine Therapy for Patients with Progressive Stage D0 Prostate Cancer »
Palliative Care Education: Focusing on Care and Not Just Disease »

Updates

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Notes »

NCI Cancer Bulletin for March 9, 2010

2010-03-09T16:31:00.000-08:00

March 9, 2010 • Volume 7 / Number 5

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News	Read This Issue

Experimental Drug Benefits Patients with Advanced Prostate Cancer »
Internal Radiation Effectively Reduces Local Recurrence of Some Endometrial Cancers »
Extensive Lymph Node Removal May Improve Survival in Some Women with Endometrial Cancer »
Children and Teens Less Likely Than Young Adults to Die of Non-Hodgkin Lymphoma »
Older Women Are at Low Risk of New HPV Infections, Infections that Progress to Cervical Cancer »
People Continue to Trust Physicians, Despite Increasing Health Information Online »

Commentary

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Director's Update: Mapping a Strategic Scientific Vision for the National Cancer Program »

In Depth

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Searching for Commonalities between Two Deadly Lung Diseases »
The Heart: An Unintended Victim of Some Targeted Cancer Therapies »
Featured Clinical Trial: Extending Targeted Immune Depletion to Unrelated Cord Blood Transplantation »

Updates

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Legislative Update »
FDA Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for February 23, 2010

2010-02-23T15:53:00.000-08:00

February 23, 2010 • Volume 7 / Number 4

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News	Read This Issue

Shorter Course of Radiation Effective and Safe for Some Women with Early-stage Breast Cancer »
Lower-dose Radiation Regimen for Breast Cancer Less Harmful to Quality of Life »
Chemo-switch Plus Sorafenib Regimen Shows Promise in Advanced Kidney Cancer »
Scientists Map Gains, Losses of DNA in Thousands of Tumors »
Researchers Learn How a microRNA May Promote the Spread of Breast Cancer »

Commentary

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Guest Director's Update: Working within Radiation Oncology to Maximize Benefits and Minimize Harms »

In Depth

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Personalizing Biomarkers for Cancer »
Chemotherapy-induced Peripheral Neuropathy »
Featured Clinical Trial: Treating Pain from Chemotherapy-induced Peripheral Neuropathy »
Preventing Cancer by Taking Steps to Reduce Childhood Obesity »

Updates

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FDA Update »
Notes »

NCI Cancer Bulletin for February 9, 2010

2010-02-09T15:18:00.001-08:00

February 9, 2010 • Volume 7 / Number 3

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News	Read This Issue

Melanoma Drugs Have Unintended Effects in Some Tumors »
Symptoms of Ovarian Cancer May Not Help Early Detection »
Trastuzumab Benefits Women with Locally Advanced, Inflammatory Breast Cancer »
Tumor-targeting Antibodies Against Glycoproteins May Be Markers of Early Cancer »
Gene Mutation Linked to Poor Survival in Children with Medulloblastoma »

Commentary

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Guest Director's Update: Join the Cancer.gov Evolution »

In Depth

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Experts Recommend Steps to Increase Colorectal Cancer Screening in Primary Care »
Profiles in Cancer Research: Dr. Raju Kucherlapati »
Cancer Center Profile: The University of Texas M. D. Anderson Cancer Center »
Featured Clinical Trial: Optimizing Chemotherapy with Bevacizumab for Ovarian Cancer »
Operation Cessation: Curbing Military and Veteran Tobacco Use »

Updates

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FDA Update »
NIH Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for January 26, 2010

2010-01-26T16:10:00.000-08:00

January 26, 2010 • Volume 7 / Number 2

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St. Jude, Washington University Launch Genome Project for Childhood Cancers »
Adjuvant Chemotherapy May Benefit Older Patients with Colorectal Cancer »
Brain Cancer, Like Other Cancers, Has Distinct Subtypes »
Strategy May Enhance Umbilical Cord Blood Transplants »
Acupuncture Reduces Joint Pain in Some Women with Breast Cancer »
Genome Scans for Pancreatic Cancer Yield Clues to Risk »

Commentary

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Guest Director's Update: Major Grant Application Changes Now in Effect »
A Conversation about Sequencing Cancer Genomes with Dr. Elaine Mardis »

In Depth

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Trials Point to Potential Advances in Lung Cancer Treatment »
Helping Breast Cancer Gene Mutation Carriers Weigh Prevention Choices »
The Downside of Diagnostic Imaging »
Featured Clinical Trial: Adjuvant Bevacizumab and Chemotherapy for High-risk Breast Cancer »
Chinese and American Scientists Meet to Discuss Environmental Causes of Cancer »

Updates

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Cancer.gov Update »
Notes »

NCI Cancer Bulletin for January 12, 2010

2010-01-12T16:15:00.000-08:00

January 12, 2010 • Volume 7 / Number 1

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Physicians Urged to Consider Active Surveillance in Prostate Cancer »
Study Weighs Comparative Effectiveness of Low-risk Prostate Cancer Treatments »
Lenalidomide Helps Delay Progression of Multiple Myeloma »
Genetic Study of Lymphoma Tumors Points to Possible Therapies »
Vaccine Kills Residual Leukemia Cells in Patients Treated with Imatinib »
Cancer Cells Use Stored Fats to Fuel Aggressive Growth and Spread »

Commentary

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Guest Director's Update: Targeting Barriers, including Insurance Coverage, to Improve Clinical Trial Participation »
Guest Commentary by Brenda Nevidjon: Health Care Changes—How Cancer Care Initiatives Can Help »

In Depth

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Ovarian Cancer Study Tests Lead Time of Potential Biomarkers »
New Cancer Drugs Bring New Side Effects, and Nurses Respond »
Video Eases End-of-Life Care Discussions »
Featured Clinical Trial: PARP Inhibitor and Metronomic Chemotherapy for Refractory Cancer »

Updates

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CDC Update »
Notes »

Happy New Year from the NCI Cancer Bulletin

2009-12-29T12:47:00.000-08:00

December 29, 2009

Dear NCI Cancer Bulletin Subscriber,

The editors, writers, and technical staff of the NCI Cancer Bulletin would like to wish each of you a happy and healthy new year.

Before we embark on our 7th year of publication, here is a list of the 10 most popular and frequently viewed NCI Cancer Bulletin feature stories of 2009:

Delving Into Possible Mechanisms for Chemobrain (March 24)
Cancer Survivors and Their Doctors Have Different Expectations about Care (April 7)
New Lung Cancer Treatment Approach Raises Hopes and Debate (July 28)
Cutting Calories to Prevent Cancer (July 14)
In Cancer, Hitting a Target Called Hedgehog (September 8)
Ovarian Cancer Markers Validated for Early Detection (April 21)
Moving Ahead with the Stimulus Funds (February 24)
Treatment Approach Using Radiofrequency Waves Heats Up (March 24)
Dietary Supplements and Cancer Treatment: A Risky Mixture (August 11)
Independent Task Force Updates Recommendations on Breast Cancer Screening (November 17)

In addition to covering the timely news stories in 2009, we launched a new online format that took advantage of the latest Web technologies, including navigation options and graphical presentations. We also introduced a number of video and audio features, such as Inside NCI and In Their Own Words, to enhance our in-depth articles. And we have expanded the options for readers to better engage our content by using RSS and, in the near future, Twitter feeds.

Looking ahead to 2010, we plan on adding additional interactive features in an effort to enhance your reading experience and better serve your information needs.

So thank you again for your interest and support in 2009. We hope you'll continue to read each issue in 2010 and encourage others to subscribe. We also appreciate your story ideas and welcome more suggestions in the coming months, which you can send to us by e-mail at ncicancerbulletin@mail.nih.gov.

Best regards,

The NCI Cancer Bulletin Team

NCI Cancer Bulletin for December 15, 2009

2009-12-15T16:15:00.001-08:00

December 15, 2009 • Volume 6 / Number 24

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Trial Suggests New First-line Treatment Option for Slow-growing Lymphomas »
Bone Drugs Linked to Fewer Cases of Breast Cancer »
U.S. Cancer Cases and Deaths Continued to Decline in 2006 »
Nilotinib Effective and Safe in Initial Treatment of Chronic Leukemia »
Androgen Deprivation Therapy Linked to Cardiovascular Disease, Diabetes »
Antioxidant Supplement May Prevent Return of Precancerous Colorectal Growths »

Commentary

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Director's Update: Modeling a Future without Cancer »
Guest Commentary by Dr. Alan G. Thorson: Moving Toward a World with Less Cancer and More Birthdays »

In Depth

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Adapting the Science of Supplements and Cancer Prevention »
Putting Circulating Tumor Cells to the Test »
Featured Clinical Trial: Defining Optimal Therapy for Metastatic and Recurrent Cervical Cancer »
Cancer Center Profile: St. Jude Children's Research Hospital Comprehensive Cancer Center »

Updates

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Notes »

NCI Cancer Bulletin for December 1, 2009

2009-12-01T16:17:00.000-08:00

December 1, 2009 • Volume 6 / Number 23

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Commentary

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Director's Update: Success Against Cancer Depends on a Vibrant, Well-trained Workforce »
Inside NCI: A Conversation with Dr. Jonathan Wiest about Cancer Research Training »

News	Read This Issue

Academia and Beyond: Supporting the Biomedical Workforce of the Future »
Intramural Training at NCI: A Wealth of Opportunities »
Ensuring a Diverse Cancer Research Workforce »
Catalyzing a National Shift toward Translational Research »
NCI Trains Future International Research Leaders »
Opportunities in a Nontraditional but Much-needed Science Workforce »
Oncology Training Resources »

Highlights

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Cervical Cancer Screening Can Be Done Later and Less Often, According to ACOG »
Long-term Follow-up Provides New Insights on Adjuvant Therapy for Lung Cancer »
No Evidence that Hookah Smoking Is Less Harmful than Cigarette Smoking »
No Significant Change in Smoking Rate from 2007 to 2008 »
Home Care Nursing Improves Cancer Symptom Management »

Updates

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Cancer.gov Update »
Notes »

NCI Cancer Bulletin for November 17, 2009

2009-11-17T15:49:00.000-08:00

November 17, 2009 • Volume 6 / Number 22

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Independent Task Force Updates Recommendations on Breast Cancer Screening »
New Drug Blocks "Undruggable" Target in Cancer Cells »
Treatment for Pancreatic Cancer May Target Tumor Microenvironment »
Survey Finds Pain Is Common Years after Breast Cancer Surgery »
Hormone Therapy Use Linked to Benign Breast Condition »
Targeted Treatment Shows Promise for Older Patients with Advanced Leukemia »
Potential Strategy for Treating Diffuse Large B-cell Lymphoma Found »

Commentary

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Guest Director's Update: Modeling for Research Success »

In Depth

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Exploring the Reasons Women Choose Mastectomies »
Featured Clinical Trial: Combination Therapy for Patients with Myelodysplastic Syndromes »
U.S.-China Cancer Research Collaborations to Be Expanded »

Updates

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FDA Update »
Cancer.gov Update »
Notes »

NCI Cancer Bulletin for November 3, 2009

2009-11-03T15:08:00.000-08:00

November 3, 2009 • Volume 6 / Number 21

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Pancreatic Cancer Report Urges Changes in Clinical Trials »
Even With Very Small Breast Tumors, Studies Find HER2 Status Matters »
Risk of Contralateral Breast Cancer Estimated for BRCA Families »
Lower Total Blood Cholesterol Levels Are Not Linked to Higher Cancer Risk »
Tests for Catching Cervical Precancers Show Equivalent Accuracy »
Nicotine Patch and Lozenge Combination Helps Smokers Quit for Longer »
Personalized Phone Counseling Helps Teens Quit Smoking »

Commentary

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Guest Director's Update: Entering a New Era in Tobacco Control Research »

In Depth

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How Gene Fusions May Occur in Prostate Cancer »
Profiles in Cancer Research: Dr. Marcia R. Cruz-Correa »
Featured Clinical Trial: Combining Chemotherapy and a PARP Inhibitor for
Advanced Solid Tumors »
Local Partners Study Mobile Support for DC Tobacco Quitline »

Updates

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Cancer.gov Update »
Notes »

NCI Cancer Bulletin for October 20, 2009

2009-10-20T15:02:00.000-07:00

October 20, 2009 • Volume 6 / Number 20

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Better Options for Children with Difficult-to-Treat Leukemia »
Minimally Invasive Prostate Cancer Surgery Shows Benefits, Shortcomings »
Liver Cancer Study Finds Potential Marker for Treatment »
Gene Mutation Linked to Aggressive Childhood Cancer »
Primary and Metastatic Tumors from Same Patient Sequenced »
Prostate Tumor Microenvironment Found to Change Immune Cell's Function »

Commentary

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Guest Director's Update: The NExT Steps in Drug Development at NCI »

In Depth

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Duplicated Gene May Explain Rare Cancer in Some Families »
Does Mammography Sometimes Detect Too Much Breast Cancer? »
Featured Clinical Trial: Testing Satraplatin in Advanced Prostate Cancer »
Cancer Center Profile: University of Chicago Cancer Research Center »

Updates

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Legislative Update »
FDA Update »
Notes »