Happy New Year from the NCI Cancer Bulletin

December 29, 2009 Dear NCI Cancer Bulletin Subscriber, The editors, writers, and technical staff of the NCI Cancer Bulletin would like to wish each of you a happy and healthy new year. Before we embark on our 7th year of publication, here is a list of the 10 most popular and frequently viewed NCI Cancer Bulletin feature stories of 2009: Delving Into Possible Mechanisms for Chemobrain (March 24) Cancer Survivors and Their Doctors Have Different Expectations about Care (April 7) New Lung Cancer Treatment Approach Raises Hopes and Debate (July 28) Cutting Calories to Prevent Cancer (July 14) In Cancer, Hitting a Target Called Hedgehog (September 8) Ovarian Cancer Markers Validated for Early Detection (April 21) Moving Ahead with the Stimulus Funds (February 24) Treatment Approach Using Radiofrequency Waves Heats Up (March 24) Dietary Supplements and Cancer Treatment: A Risky Mixture (August 11) Independent Task Force Updates Recommendations on Breast Cancer Screening (November 17) In addition to covering the timely news stories in 2009, we launched a new online format that took advantage of the latest Web technologies, including navigation options and graphical presentations. We also introduced a number of video and audio features, such as Inside NCI and In Their Own Words, to enhance our in-depth articles. And we have expanded the options for readers to better engage our content by using RSS and, in the near future, Twitter feeds. Looking ahead to 2010, we plan on adding additional interactive features in an effort to enhance your reading experience and better serve your information needs. So thank you again for your interest and support in 2009. We hope you'll continue to read each issue in 2010 and encourage others to subscribe. We also appreciate your story ideas and welcome more suggestions in the coming months, which you can send to us by e-mail at ncicancerbulletin@mail.nih.gov. Best regards, The NCI Cancer Bulletin Team

NCI Cancer Bulletin for December 15, 2009

December 15, 2009 • Volume 6 / Number 24 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Trial Suggests New First-line Treatment Option for Slow-growing Lymphomas »  Bone Drugs Linked to Fewer Cases of Breast Cancer »  U.S. Cancer Cases and Deaths Continued to Decline in 2006 »  Nilotinib Effective and Safe in Initial Treatment of Chronic Leukemia »  Androgen Deprivation Therapy Linked to Cardiovascular Disease, Diabetes »  Antioxidant Supplement May Prevent Return of Precancerous Colorectal Growths »  Commentary Read This Issue Director's Update: Modeling a Future without Cancer » Guest Commentary by Dr. Alan G. Thorson: Moving Toward a World with Less Cancer and More Birthdays » In Depth Read This Issue Adapting the Science of Supplements and Cancer Prevention »  Putting Circulating Tumor Cells to the Test »  Featured Clinical Trial: Defining Optimal Therapy for Metastatic and Recurrent Cervical Cancer »  Cancer Center Profile: St. Jude Children's Research Hospital Comprehensive Cancer Center »  Updates Read This Issue Notes »

NCI Cancer Bulletin for December 1, 2009

December 1, 2009 • Volume 6 / Number 23 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. Commentary Read This Issue Director's Update: Success Against Cancer Depends on a Vibrant, Well-trained Workforce »  Inside NCI: A Conversation with Dr. Jonathan Wiest about Cancer Research Training »  News Read This Issue Academia and Beyond: Supporting the Biomedical Workforce of the Future »  Intramural Training at NCI: A Wealth of Opportunities »  Ensuring a Diverse Cancer Research Workforce »  Catalyzing a National Shift toward Translational Research »  NCI Trains Future International Research Leaders »  Opportunities in a Nontraditional but Much-needed Science Workforce »  Oncology Training Resources »  Highlights Read This Issue Cervical Cancer Screening Can Be Done Later and Less Often, According to ACOG »  Long-term Follow-up Provides New Insights on Adjuvant Therapy for Lung Cancer »  No Evidence that Hookah Smoking Is Less Harmful than Cigarette Smoking »  No Significant Change in Smoking Rate from 2007 to 2008 »  Home Care Nursing Improves Cancer Symptom Management »  Updates Read This Issue Cancer.gov Update »  Notes »

NCI Cancer Bulletin for November 17, 2009

November 17, 2009 • Volume 6 / Number 22 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Independent Task Force Updates Recommendations on Breast Cancer Screening »  New Drug Blocks "Undruggable" Target in Cancer Cells »  Treatment for Pancreatic Cancer May Target Tumor Microenvironment »  Survey Finds Pain Is Common Years after Breast Cancer Surgery »  Hormone Therapy Use Linked to Benign Breast Condition »  Targeted Treatment Shows Promise for Older Patients with Advanced Leukemia »  Potential Strategy for Treating Diffuse Large B-cell Lymphoma Found »  Commentary Read This Issue Guest Director's Update: Modeling for Research Success » In Depth Read This Issue Exploring the Reasons Women Choose Mastectomies »  Featured Clinical Trial: Combination Therapy for Patients with Myelodysplastic Syndromes »  U.S.-China Cancer Research Collaborations to Be Expanded »  Updates Read This Issue FDA Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for November 3, 2009

November 3, 2009 • Volume 6 / Number 21 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Pancreatic Cancer Report Urges Changes in Clinical Trials »  Even With Very Small Breast Tumors, Studies Find HER2 Status Matters »  Risk of Contralateral Breast Cancer Estimated for BRCA Families »  Lower Total Blood Cholesterol Levels Are Not Linked to Higher Cancer Risk »  Tests for Catching Cervical Precancers Show Equivalent Accuracy »  Nicotine Patch and Lozenge Combination Helps Smokers Quit for Longer »  Personalized Phone Counseling Helps Teens Quit Smoking »  Commentary Read This Issue Guest Director's Update: Entering a New Era in Tobacco Control Research » In Depth Read This Issue How Gene Fusions May Occur in Prostate Cancer »  Profiles in Cancer Research: Dr. Marcia R. Cruz-Correa »  Featured Clinical Trial: Combining Chemotherapy and a PARP Inhibitor for Advanced Solid Tumors »  Local Partners Study Mobile Support for DC Tobacco Quitline »  Updates Read This Issue Cancer.gov Update »  Notes »

NCI Cancer Bulletin for October 20, 2009

October 20, 2009 • Volume 6 / Number 20 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Better Options for Children with Difficult-to-Treat Leukemia »  Minimally Invasive Prostate Cancer Surgery Shows Benefits, Shortcomings »  Liver Cancer Study Finds Potential Marker for Treatment »  Gene Mutation Linked to Aggressive Childhood Cancer »  Primary and Metastatic Tumors from Same Patient Sequenced »  Prostate Tumor Microenvironment Found to Change Immune Cell's Function »  Commentary Read This Issue Guest Director's Update: The NExT Steps in Drug Development at NCI » In Depth Read This Issue Duplicated Gene May Explain Rare Cancer in Some Families »  Does Mammography Sometimes Detect Too Much Breast Cancer? »  Featured Clinical Trial: Testing Satraplatin in Advanced Prostate Cancer »  Cancer Center Profile: University of Chicago Cancer Research Center »  Updates Read This Issue Legislative Update »  FDA Update »  Notes »

NCI Cancer Bulletin for October 6, 2009

October 6, 2009 • Volume 6 / Number 19 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue The Cancer Genome Atlas Project to Map 20 Tumor Types »  Hormone Therapy for Prostate Cancer May Pose Heart Risks »  Breast Cancer Trial Suspends Recruitment »  High-dose Daunorubicin Benefits Younger Adults with Leukemia »  Many Survivors of Childhood Cancers Have Healthy Babies »  Investigational Drug Effective Against Metastatic Melanoma in Early Phase Trial »  Invasiveness of Breast Cancer Cells Linked to Two Proteins »  Commentary Read This Issue Director's Update: Global Cancer Control: An Essential Duty » In Depth Read This Issue Experts Tackle the Challenge of Managing Ductal Carcinoma In Situ »  Adapting Capsule Endoscopy for Colorectal Cancer Screening »  Featured Clinical Trial: Targeting HER2 in the Treatment of Ductal Carcinoma In Situ »  Spokes of Hope: Surviving Cancer and Riding On »  Updates Read This Issue Cancer.gov Update »  Notes »

NCI Cancer Bulletin for September 22, 2009

September 22, 2009 • Volume 6 / Number 18 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Modified Chemo Regimen Effective in Advanced Ovarian Cancer »  Diabetes Drug Metformin Shows Promise as a Breast Cancer Treatment »  Hormone Therapy Linked to Risk of Death from Lung Cancer »  Recently Discovered Virus Linked to Aggressive Prostate Tumors »  Fat Cells Interfere with Chemotherapy for Leukemia »  Hepatitis B Vaccine Lowers Risk of Liver Cancer »  Commentary Read This Issue Director's Update: Using ARRA Funds to Advance Cancer Research » In Depth Read This Issue Charting the Path from Infection to Cancer »  Harnessing the Biological Activity of Natural Products »  Profiles in Cancer Research: Dr. Jun S. Wei »  Featured Clinical Trial: Comparing Drug Regimens for Diffuse Large B-cell Lymphoma »  Updates Read This Issue FDA Update »  Notes »

NCI Cancer Bulletin for September 8, 2009

September 8, 2009 • Volume 6 / Number 17 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Study Questions Value of Prostate Cancer Screening »  Genetic Study Points to Potential Treatment for Melanoma »  Chemotherapy Provides Longer Survival than Enzyme Therapy for Pancreatic Cancer »  Denosumab Keeps Bones Strong during Prostate Cancer Treatment »  Weight Lifting Reduces Lymphedema Symptoms after Breast Cancer »  In West African Women, Majority of Breast Cancers Have a Poor Prognosis »  Commentary Read This Issue Guest Director's Update: Finding the Right Mix of Care Providers for Cancer Patients » A Conversation about Personal Genomic Tests with Dr. Muin Khoury » In Depth Read This Issue In Cancer, Hitting a Target Called Hedgehog »  Growing Pains: Palliative Care Making Gains »  Proton Therapy for Cancer: A New Technology Brief »  Featured Clinical Trial: Testing a New Drug in Advanced BRCA-related Cancer »  Updates Read This Issue FDA Update »  Notes »

NCI Cancer Bulletin for August 25: Top 10 feature stories since January

August 25, 2009 Dear NCI Cancer Bulletin Subscriber, The editors, writers, and technical staff of the NCI Cancer Bulletin would like to thank each of you for your continued interest in our newsletter. There is no issue today due to our summer publication break. We will resume publication on September 8. In the meantime, we have compiled the list below of our most popular feature stories so far this year, according to page views: Moving Ahead with the Stimulus Funds (Director’s Update, February 24) Cancer Survivors and Their Doctors Have Different Expectations about Care (Featured Article, April 7) Years Before Myeloma, Blood Shows Changes (Featured Article, February 24) Delving Into Possible Mechanisms for Chemobrain (A Closer Look, March 24) Ovarian Cancer Markers Validated for Early Detection (Featured Article, April 21) Treatment Approach Using Radiofrequency Waves Heats Up (Spotlight, March 24) Putting Some Perspective on Research and Risk (Director’s Update, June 30) Cervical Cancer Screening with HPV Test Reduces Advanced Cancers, Death (Special Report, April 7) Cutting Calories to Prevent Cancer (A Closer Look, July 14) Studies Suggest Unintended Consequences of Angiogenesis Inhibition (Spotlight, April 21) Thank you again for your interest and support. We hope you'll continue to read each issue and encourage others to subscribe. We also appreciate your story ideas and welcome more suggestions in the coming months, which you can send to us by e-mail at ncicancerbulletin@mail.nih.gov. Best regards, The NCI Cancer Bulletin Team

NCI Cancer Bulletin for August 11, 2009

August 11, 2009 • Volume 6 / Number 16 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue HPV Infection Drives Disparity in Head and Neck Cancer Survival »  Blood Type Influences Pancreatic Cancer Risk »  Second Cancer Patient has Genome Sequenced »  Many Prostatectomy Patients Face Low Risk of Prostate Cancer Death »  Low Glucose around Tumors Can Cause Cancer-fueling Mutations »  Review Finds No Firm Evidence that Green Tea Prevents Cancer »  Cancer Incidence in U.S. Hispanics Varies by Country of Origin »  Commentary Read This Issue Director's Update: ACTNOW Opens the Gate for Timely, Novel Research » A Conversation With…Dr. James Doroshow » In Depth Read This Issue Dietary Supplements and Cancer Treatment: A Risky Mixture »  Cancer Center Profile: UCSF Helen Diller Family Comprehensive Cancer Center »  Featured Clinical Trial: Refining Treatment for High-risk Early Stage Endometrial Cancer »  NCI Plans to Expand Outreach through Community-based Research Programs »  Updates Read This Issue NIH Update »  FDA Update »  Notes »

NCI Cancer Bulletin for July 28, 2009

July 28, 2009 • Volume 6 / Number 15 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue More Women Are Choosing Mastectomies at Mayo Clinic »  Breast Cancer Risk in Survivors of Childhood Cancer Quantified »  Thalidomide Does Not Help in Small Cell Lung Cancer »  New Role Found for Tumor-suppressor Protein »  Clinical Trial Caution: Meeting Abstract May Differ from Final Publication »  Commentary Read This Issue Director's Update: A Significant Milepost on the Cancer Informatics Super Highway » In Depth Read This Issue New Lung Cancer Treatment Approach Raises Hopes and Debate »  Supportive Care Trials Face Challenge of Scientific and Ethical Inadequacies »  Study Supports Use of Existing Technology for Clinical Proteomics Research »  Featured Clinical Trial: Comparing Second-line Therapies for Advanced Lung Cancer »  Updates Read This Issue FDA Update »  Notes »

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Gastrointestinal Cancer

What is gastrointestinal cancer? Learn more about the types, causes, symptoms, and treatment of gastrointestinal cancer.

Treating HPV

A look into how HPV is treated and under what circumstances is no treatment is recommneded.