Seasons Greetings

December 28, 2010 Dear NCI Cancer Bulletin Subscriber, The editors, writers, and technical staff of the NCI Cancer Bulletin would like to wish each of you a safe and joyous holiday season and a happy and healthy new year. Next month, we will begin our eighth year of publication. Since launching in 2004, we have published nearly 250 issues and well over 3,500 cancer research news stories, all of which can be accessed through our archive/search page. Last year in particular brought a host of important news and feature stories. Many of these are included in our "2010 Editors' Picks" list. We chose these stories not only for their potential impact on clinical practice, but also for their value as important but underreported topics. Finally, here is a sneak peek at our 2010 reader satisfaction survey results, which will also be posted in our first issue of 2011. Thanks to all who participated and sent in suggestions and comments. The overall results mirror our 2007 survey and, while there are obvious limitations with any voluntary survey, we believe the data and suggestions will help inform our future plans for the newsletter as we strive to meet reader needs and expectations. Thank you again for your interest and support in 2010. We hope you'll continue to read each issue and encourage others to subscribe. Best regards, The NCI Cancer Bulletin Team

NCI Cancer Bulletin for December 14, 2010

December 14, 2010 • Volume 7 / Number 24 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue New Surgeon General's Report Outlines How Tobacco Smoke Causes Disease »  Study Estimates More than 600,000 Deaths Worldwide Caused by Secondhand Smoke »  Zoledronic Acid Does Not Improve Disease-Free Survival in Breast Cancer »  Regular Sunscreen Use May Reduce Invasive Melanoma Risk »  Hormone Therapy for Low-Risk Prostate Cancer Declines When Medicare Reimbursements Are Reduced »  Study Shows Strong Link between Obesity and Mortality »  New Subtype of Acute Myeloid Leukemia Identified »  Screening Compliance, Stage of Cancers Detected Vary by Demographic »  Commentary Read This Issue A Conversation with Dr. James Doroshow about NCI's Clinical Trials Cooperative Group Program » In Depth Read This Issue Trial Suggests New Treatment Option for Hodgkin Lymphoma »  Featured Clinical Trial: Targeting Tumor Metabolism in Papillary Kidney Cancers »  Statistical Strength in Numbers: International Clinical Trials for Rare Cancers »  Updates Read This Issue FDA Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for November 30, 2010

November 30, 2010 • Volume 7 / Number 23 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. Commentary Read This Issue Where Science Meets Culture: The Art of Health Diplomacy »  News Read This Issue In Bangladesh, Developing Models for Cancer Care »  The Cancer Expert Corps: An Idea for Building Human Capital »  Cancer Communicators in Latin America Get Support at NCI Workshop »  Considering Culture When Providing Cancer Care »  NCI’s International Cancer Research Resources »  Highlights Read This Issue Prostate Cancer Hormone Treatments May Raise Risk of Colorectal Cancer »  Strategy to Screen for Lynch Syndrome May Save Lives and Be Cost Effective »  Anemia Drug May Interfere with Trastuzumab’s Anticancer Effects »  Possible Causes of Resistance to Melanoma Drug Reported »  Radiation Treatment for Head and Neck Cancer May Produce Hearing Loss »  Updates Read This Issue FDA Update »  CMS Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for November 16, 2010

November 16, 2010 • Volume 7 / Number 22 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: HHS Releases New Tobacco Control Strategy for the Nation »  Mutated Gene Linked to Poor Survival in Acute Myeloid Leukemia »  Novel Drug Effectively Shrinks Tumors in Hodgkin Lymphoma »  Indefinite Imatinib Therapy May Not Be Necessary for Some CML Patients »  Lasofoxifene Is Potential New Option for Breast Cancer Risk Reduction »  Some Cells in Stroma May Block Immune System's Antitumor Effects »  In Depth Read This Issue Low-Dose CT Shows Clear Mortality Benefit for Lung Cancer Screening in Heavy Smokers »  Uncertain Road for Potential Ewing Sarcoma Therapy »  Featured Clinical Trial: Combination Therapy for Advanced Kaposi Sarcoma »  Families and Scientists Gather to Discuss Research and Treatment for Li-Fraumeni Syndrome »  Updates Read This Issue Legislative Update »  Cancer.gov Update »  Notes »

Breaking News from the NCI Cancer Bulletin

November 4, 2010 Lung Cancer Trial Results Show Mortality Benefit with Low-Dose CT NCI has released initial results from the National Lung Screening Trial (NLST), a randomized national trial involving more than 53,000 current and former heavy smokers ages 55 to 74. The trial compared the effects of two lung cancer screening procedures—low-dose helical computed tomography (CT) and standard chest X-ray—on lung cancer mortality and found 20 percent fewer lung cancer deaths among trial participants screened with low-dose helical CT.  Read more >>

NCI Cancer Bulletin for November 2, 2010

November 2, 2010 • Volume 7 / Number 21 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Crizotinib Continues to Show Promise for Some Lung Tumors, Faces Challenge of Drug Resistance »  Pancreatic Cancers May Develop Slowly Over Many Years »  Cetuximab May Benefit Some Patients with KRAS Gene Mutations »  Protein Found on Tumor Blood Vessels Might Be Cancer Target »  More Evidence Suggests Aspirin May Prevent Colorectal Cancer »  In Depth Read This Issue Engineering Progress against a Rare Cancer »  Featured Clinical Trial: Targeted Antibody Therapy for Metastatic Adrenocortical Carcinoma »  Recognition of Animal Welfare in Biomedical Science Takes Center Stage »  Updates Read This Issue FDA Update »  Notes »

NCI Cancer Bulletin for October 19, 2010

October 19, 2010 • Volume 7 / Number 20 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Cancer Screening Continues Even after Patients Are Diagnosed with Terminal Cancer »  Abiraterone Improves Survival in Metastatic Prostate Cancer »  Similar Early-phase Trials Prohibit Different Drugs, Undermining Outcomes »  Surgical Procedure Reduces Disability and Pain Caused by Spine Fractures in Cancer Patients »  Commentary Read This Issue Guest Commentary: Bringing Science to the Market » In Depth Read This Issue Hormone Therapy Linked to Modest Increase in Breast Cancer Deaths »  Testing a "Smarter" Biopsy for Prostate Cancer »  Partners in Crime: Using Synthetic Lethality to Identify New Cancer Targets »  Featured Clinical Trial: Eliminating Hairy Cell Leukemia Minimal Residual Disease »  Updates Read This Issue FDA Update »  HHS Update »  Notes »

NCI Cancer Bulletin Survey Reminder

October 6, 2010 Dear Reader, Time is running out for your participation in the NCI Cancer Bulletin reader survey. Subscribers like you are a key source of information on how to improve the newsletter and help ensure that the needs of readers are met. If you have already completed the survey, thank you and please disregard the rest of this message. If you have not yet completed the survey, we would like to invite you one last time to click here to complete the survey no later than Tuesday, October 12, 2010. The survey should take you about 5–10 minutes to complete and your responses will be anonymous. Thank you in advance for your participation. We welcome your input and look forward to sharing the results of the survey in an upcoming issue of the NCI Cancer Bulletin. Sincerely, The NCI Cancer Bulletin Staff

NCI Cancer Bulletin for October 5, 2010

October 5, 2010 • Volume 7 / Number 19 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Experts Urge Further Research on Nicotine Reduction to Decrease Tobacco Addiction »  Less-invasive Lymph Node Surgery Safe for Women with Breast Cancer »  HPV Screen-and-Treat Methods Prevent Cervical Cancer Precursors in Low-resource Settings »  Black Patients with Advanced Cancer Are More Likely to Receive Unwanted Care at End of Life »  Genetic Study Finds Clue to Gastrointestinal Stromal Tumors »  In Depth Read This Issue Studies Provide New Data on Mammography and Breast Cancer Mortality »  Turning the Immune System against a Childhood Cancer »  Featured Clinical Trial: Preventing Chemotherapy-related Hearing Loss in Young Cancer Patients »  Profiles in Cancer Research: Dr. Pier Paolo Pandolfi »  Physician Assistants Valued for Patient Care and Research Support at NCI »  Updates Read This Issue Cancer.gov Update »  Notes »

NCI Cancer Bulletin Survey Reminder

September 28, 2010 Dear Reader, The National Cancer Institute (NCI) is gathering feedback on the NCI Cancer Bulletin. Subscribers like you are a key source of information on how to improve the newsletter and help ensure that the needs of readers are met. We hope you will choose to participate in the survey.  If you have already completed the survey, thank you and please disregard the rest of this message. If you have not yet completed the survey, please click here to complete the survey no later than Tuesday, October 12, 2010. It will take approximately 10 minutes to complete and your responses will be anonymous. Thank you in advance for your participation. We welcome your input and look forward to sharing the results of the survey in an upcoming issue of the NCI Cancer Bulletin. Sincerely, The NCI Cancer Bulletin Staff

NCI Cancer Bulletin for September 21, 2010

September 21, 2010 • Volume 7 / Number 18 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Drug Protects Heart in Children Receiving Common Chemotherapy »  Mutations Linked to Two Uncommon Forms of Ovarian Cancer »  Declines in U.S. Smoking Prevalence Stalled »  Men with Low PSA Levels May Not Benefit from Further Prostate Cancer Screening »  Hospitalization Near Death May Diminish Mental Health of Caregivers and Quality of Life for Cancer Patients »  In Depth Read This Issue When Ovarian Cancer Returns Years Later »  XMRV Researchers Discuss the State of the Science »  Featured Clinical Trial: Combining Vaccine and Antiandrogen Therapy for Prostate Cancer »  Quitting Smoking? Find Support on Facebook »  Updates Read This Issue Cancer.gov Update »  FDA Update »  Notes »

NCI Cancer Bulletin Survey

September 14, 2010 Dear Reader, The National Cancer Institute (NCI) has been publishing the NCI Cancer Bulletin since 2004. We regard you, the subscriber, as an important source of information on how to improve the newsletter and help ensure that the needs of readers are met. We would appreciate your participation in a brief survey to gather feedback on the NCI Cancer Bulletin. Your comments are extremely valuable. Please click here to complete the survey no later than Tuesday, October 12, 2010. The survey will take approximately 10 minutes to complete, and your responses will be anonymous. Thank you in advance for your comments. We welcome your input and look forward to sharing the results of the survey in an upcoming issue of the NCI Cancer Bulletin. Sincerely, The NCI Cancer Bulletin Staff

NCI Cancer Bulletin for September 7, 2010

September 7, 2010 • Volume 7 / Number 17 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Targeted Drug for Melanoma Shows Promise in Early Clinical Testing »  For Women with BRCA Mutations, Prophylactic Surgery Reduces Cancer Risk »  Less-intensive Treatment Regimen Effective against Multiple Myeloma »  Lower-dose Treatments for Early-stage Hodgkin Lymphoma Do Not Compromise Results »  Chemotherapy Affects Brain Structure of Breast Cancer Patients »  Consuming High Levels of Red Meat and Fat May Increase Liver Cancer Risk »  Cancer Patients Leaving Hospice Early Boost Medicare Expenditures »  Commentary Read This Issue Inside NCI: A Conversation with Dr. Crystal Mackall about Pediatric Oncology »  In Depth Read This Issue Palliative Care Improves Survival, Quality of Life in Advanced Lung Cancer »  Autophagy: The Strange Dining Habits of Cancer Cells »  Featured Clinical Trial: Comparing Post-transplant Therapies for Multiple Myeloma Patients »  Updates Read This Issue Notes »

NCI Cancer Bulletin: Top 10 Feature Stories Since January

August 24, 2010 Dear NCI Cancer Bulletin Subscriber, The editors, writers, and technical staff of the NCI Cancer Bulletin would like to thank each of you for your continued interest in our newsletter. We will not publish an issue today due to our summer production break, but we will resume biweekly publication on September 7. In the meantime, we have compiled a list below of the 10 most popular feature-length stories published so far this year, according to reader page views: FDA Approves First Therapeutic Cancer Vaccine (May 4) Physicians Urged to Consider Active Surveillance in Prostate Cancer (Jan. 12) Experimental Drug Benefits Patients with Advanced Prostate Cancer (Mar. 9) Chemotherapy-induced Peripheral Neuropathy (Feb. 23) The Downside of Diagnostic Imaging (Jan. 26) Melanoma Drugs Have Unintended Effects in Some Tumors (Feb. 9) New Cancer Drugs Bring New Side Effects, and Nurses Respond (Jan. 12) Trials Point to Potential Advances in Lung Cancer Treatment (Jan. 26) Personalizing Biomarkers for Cancer (Feb. 23) I-SPY2: Breast Cancer Trial Aims to Speed Drugs to the Clinic (Mar. 23) We are especially proud of our ability to bring you stories like these through RSS and Twitter feeds, as well as to present our content via a variety of platforms like YouTube and Facebook. In addition, for those who may prefer to read selected articles in Spanish, we have a Spanish-language version of the newsletter. Thank you again for your interest and support. We hope you’ll continue to read each issue and encourage others to subscribe. Best regards, The NCI Cancer Bulletin Team

NCI Cancer Bulletin for August 10, 2010

August 10, 2010 • Volume 7 / Number 16 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Protein Helps Predict Cancer Therapy-induced Heart Damage »  Bone Drugs Do Not Appear to Increase Esophageal or Gastric Cancer Risk »  Immune Cells' Anticancer Abilities May Be Hampered by High Lipid Levels »  microRNA May Regulate Growth of Tumor Blood Vessels »  Many U.S. and Canadian Oncologists Unprepared to Use Cost-effectiveness Data in Practice »  In Depth Read This Issue A Cancer Treatment That Sticks Around »  NCI's Cancer Information Service: Providing Information and Assistance Nationwide  »  Featured Clinical Trial: Cediranib to Treat Alveolar Soft Part Sarcoma »  The Comprehensive Cancer Center of Wake Forest University »  Updates Read This Issue Legislative Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for July 27, 2010

July 27, 2010 • Volume 7 / Number 15 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: FDA Advisory Committee Recommends against Bevacizumab for Metastatic Breast Cancer »  PSA Screening Leads to Aggressive Treatment, Even in Older Men at Low Risk »  Chemotherapy Regimen Benefits Men with Metastatic Penile Cancer »  Hormone Therapy Increases Breast Cancer Risk for Women with Dense Breasts »  Brain Cancer Incidence Trends Do Not Support Link to Cell Phones »  Expert Panel Reports on Knowledge Gaps for 20 Suspected Carcinogens »  In Depth Read This Issue The Evolving Science of Cancer Stem Cells »  When Brain Cancer Returns, New Test May Aid Decisions about Surgery »  Using e-Health Tools to Improve Quality of Life for Cancer Patients »  Profiles in Cancer Research: Dr. Carol Fabian »  Featured Clinical Trial: Electroacupuncture for Radiation-induced Chronic Dry Mouth »  Updates Read This Issue Notes »

NCI Cancer Bulletin for July 13, 2010

July 13, 2010 • Volume 7 / Number 14 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Harold Varmus Becomes Fourteenth Director of the National Cancer Institute »  Adherence Low among Women Taking Adjuvant Hormone Therapy for Early-stage Breast Cancer »  Drug that Inhibits DNA-repair Enzyme Shrinks Some Breast and Ovarian Tumors »  Colorectal Cancer Screening Rates Rise, Mammography Rates Dip Slightly in the U.S. »  Length of Telomeres Linked to Risk for Some Cancers »  Study Estimates Cancer Cases Due to Radiation Exposure in the Marshall Islands »  In Depth Read This Issue Synthetic Biology and Cancer: Exploring the Possibilities »  Can PSA Screening Decrease Prostate Cancer Mortality? »  Featured Clinical Trial: Targeting HER2 in the Treatment of Ductal Carcinoma In Situ »  Cancer Survivors Discover the Power of Blogging »  Updates Read This Issue Legislative Update »  NIH Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for June 29, 2010

June 29, 2010 • Volume 7 / Number 13 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Genome Studies Start to Unravel Prostate Cancer's Complexity »  Gefitinib Improves Outcomes for Metastatic Lung Cancers with EGFR Mutations »  Study Finds Poor Physician Adherence to Cervical Cancer Screening Guidelines »  Targeted Drug Tested in Children with Recurrent Medulloblastoma »  Vitamin D Concentrations in Blood Not Linked to Risk of Less Common Cancers »  Cancer Survivors More Likely Than Peers to Forgo Medical Care Due to Cost »  Commentary Read This Issue Guest Director's Update: Cancer Survivorship Research Conference—Recovery and Beyond » In Depth Read This Issue Guidelines Urge Exercise for Cancer Patients, Survivors »  Four Breast Cancer Trials with Clinical Implications »  Featured Clinical Trial: Inhibiting Angiogenesis in Metastatic Castration-resistant Prostate Cancer »  Updates Read This Issue FDA Update »  HHS Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for May 18, 2010

May 18, 2010 • Volume 7 / Number 10 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. Commentary Read This Issue Director's Update: For Clinical Trials, a Time of Challenge, Change, and Opportunity »  Inside NCI: A Conversation with Dr. Jeff Abrams about Cancer Clinical Trials »  News Read This Issue Cancer Trials Accrual Tool Focuses on Solutions »  Insurance Coverage Expanding for Cancer Clinical Trials »  Talking about Trials: Overcoming Bottlenecks in Clinical Communication »  Taking Action to Diversify Clinical Cancer Research »  Overcoming Age Limits in Cancer Clinical Trials »  Additional Clinical Trials Resources »  Highlights Read This Issue Study Finds No Overall Increased Brain Tumor Risk from Cell Phones »  Cost of Cancer Care in the United States Doubled in the Past 20 Years »  Liver Cancer Cases in the United States Continued to Rise Through 2006 »  Doctors Urged to Monitor Hypertension in Cancer Patients Treated with Anti-VEGF Therapies »  Updates Read This Issue Legislative Update »  Cancer.gov Update »  Notes »

Breaking News from the NCI Cancer Bulletin

May 17, 2010 President Obama to Appoint Harold Varmus, M.D., to Lead the National Cancer Institute Today, President Barack Obama announced his intent to appoint Harold Varmus, M.D., to serve as Director of the National Cancer Institute (NCI). In an e-mail to the NCI staff, Francis Collins, M.D., Ph.D., Director of the National Institutes of Health, said that Varmus "brings unmatched expertise at all levels - not only in cutting edge scientific research, but also as a leader in the development of strategies for improving patient care, in scientific education and training, and in the design of novel public-private partnerships." Read more >>

NCI Cancer Bulletin for May 4, 2010

May 4, 2010 • Volume 7 / Number 9 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue FDA Approves First Therapeutic Cancer Vaccine »  Breast Tissues May Express Biomarkers Linked to DCIS Recurrence »  Circulating Tumor Cells Detected in Patients with Localized Cancers »  Costs and Use of Diagnostic Imaging Rise among Medicare Patients »  Commentary Read This Issue Guest Director's Update: NCCCP—Building a Community-based Research Platform and Enhancing Cancer Care » In Depth Read This Issue Sigmoidoscopy Markedly Reduces Colorectal Cancer Incidence, Mortality »  When Allogeneic Stem Cell Transplants Fail »  Featured Clinical Trial: Vaccine Therapy for Patients with Recurrent Blood Cancers »  Updates Read This Issue FDA Update »  Legislative Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for April 20, 2010

April 20, 2010 • Volume 7 / Number 8 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Long-term Follow-up Confirms Breast Cancer Risk Reduction with Raloxifene »  MicroRNAs Linked to Trastuzumab Resistance, Brain Metastases »  Diabetes Drug Metformin Prevents Lung Tumors in Mice »  Cancer Risk Tools May Need Regular Recalibration »  Profiling Airway Cells May Identify Smokers at Highest Risk of Cancer »  Peptide Helps Chemotherapy Penetrate Deep into Tumors »  Commentary Read This Issue Director's Update: An Unexpected Opportunity, a Welcome Honor » Guest Commentary by Dr. Carolyn Clancy: Focusing the Research Enterprise on the Patient » In Depth Read This Issue Trial Makes Push Toward More Individualized Lung Cancer Therapy »  Genome Study of Aggressive Breast Cancer Yields Clues to Metastasis »  Featured Clinical Trial: Pioglitazone for Oral Premalignant Lesions »  IoM Committee Recommends Overhaul of NCI Clinical Trials Cooperative Group Program »  Updates Read This Issue FDA Update »  Legislative Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for April 6, 2010

April 6, 2010 • Volume 7 / Number 7 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Dutasteride Decreases Prostate Cancer Risk »  Phase III Lung and Pancreatic Cancer Trials Stopped »  Use of Health Care Services May Contribute to Colorectal Cancer Disparities »  Complementary and Alternative Medicine Commonly Used by Pediatric Patients »  Breast Cancer Study Tests Effects of Zoledronic Acid »  Commentary Read This Issue Guest Director's Update: Improving the Efficiency of Clinical Trials—Decreasing Activation Times by Fifty Percent » Guest Commentary by Ambassador Nancy Brinker: Collaborating Globally to Address Breast Cancer in Latin America » A Conversation with Dr. Robert T. Croyle on Communicating Science » In Depth Read This Issue Scientists Restore DNA Repair in Mice with BRCA1 Gene Mutations »  Focusing on Older Cancer Patients: A Clinical Need and a Research Necessity »  Featured Clinical Trial: New Chemotherapy Drug for Advanced Cervical Cancer »  Cancer Center Profile: Indiana University Melvin and Bren Simon Cancer Center »  Updates Read This Issue Legislative Update »  FDA Update »  Notes »

NCI Cancer Bulletin for March 23, 2010

March 23, 2010 • Volume 7 / Number 6 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue I-SPY2: Breast-cancer Trial Aims to Speed Drugs to the Clinic »  Many Older Colorectal Cancer Patients Do Not Receive Adjuvant Chemotherapy »  Drug Slows Progression of Cutaneous T-Cell Lymphoma »  Prognostic Marker for Hodgkin Lymphoma Could Improve Care »  Nanoparticle-based Therapy Triggers RNA Interference in Human Tumors »  Commentary Read This Issue Guest Director's Update: Improving Delivery of Quality Cancer Care » Guest Commentary by Dr. Andrea Barsevick: Fatigue—Is it Normal or Pathological? And How Can We Best Treat It? » A Conversation with Dr. Ann Berger on Palliative Care at NIH » In Depth Read This Issue Common Genetic Variants Modestly Improve Breast-cancer Risk Models »  Training Providers and Patients to Talk about End-of-Life Care »  Treating the Whole Person in the City of Hope Lung Cancer Study »  Featured Clinical Trial: Vaccine Therapy for Patients with Progressive Stage D0 Prostate Cancer »  Palliative Care Education: Focusing on Care and Not Just Disease »  Updates Read This Issue Notes »

NCI Cancer Bulletin for March 9, 2010

March 9, 2010 • Volume 7 / Number 5 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Experimental Drug Benefits Patients with Advanced Prostate Cancer »  Internal Radiation Effectively Reduces Local Recurrence of Some Endometrial Cancers »  Extensive Lymph Node Removal May Improve Survival in Some Women with Endometrial Cancer »  Children and Teens Less Likely Than Young Adults to Die of Non-Hodgkin Lymphoma »  Older Women Are at Low Risk of New HPV Infections, Infections that Progress to Cervical Cancer »  People Continue to Trust Physicians, Despite Increasing Health Information Online »  Commentary Read This Issue Director's Update: Mapping a Strategic Scientific Vision for the National Cancer Program » In Depth Read This Issue Searching for Commonalities between Two Deadly Lung Diseases »  The Heart: An Unintended Victim of Some Targeted Cancer Therapies »  Featured Clinical Trial: Extending Targeted Immune Depletion to Unrelated Cord Blood Transplantation »  Updates Read This Issue Legislative Update »  FDA Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for February 23, 2010

February 23, 2010 • Volume 7 / Number 4 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Shorter Course of Radiation Effective and Safe for Some Women with Early-stage Breast Cancer »  Lower-dose Radiation Regimen for Breast Cancer Less Harmful to Quality of Life »  Chemo-switch Plus Sorafenib Regimen Shows Promise in Advanced Kidney Cancer »  Scientists Map Gains, Losses of DNA in Thousands of Tumors »  Researchers Learn How a microRNA May Promote the Spread of Breast Cancer »  Commentary Read This Issue Guest Director's Update: Working within Radiation Oncology to Maximize Benefits and Minimize Harms » In Depth Read This Issue Personalizing Biomarkers for Cancer »  Chemotherapy-induced Peripheral Neuropathy »  Featured Clinical Trial: Treating Pain from Chemotherapy-induced Peripheral Neuropathy »  Preventing Cancer by Taking Steps to Reduce Childhood Obesity »  Updates Read This Issue FDA Update »  Notes »

NCI Cancer Bulletin for February 9, 2010

February 9, 2010 • Volume 7 / Number 3 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Melanoma Drugs Have Unintended Effects in Some Tumors »  Symptoms of Ovarian Cancer May Not Help Early Detection »  Trastuzumab Benefits Women with Locally Advanced, Inflammatory Breast Cancer »  Tumor-targeting Antibodies Against Glycoproteins May Be Markers of Early Cancer »  Gene Mutation Linked to Poor Survival in Children with Medulloblastoma »  Commentary Read This Issue Guest Director's Update: Join the Cancer.gov Evolution » In Depth Read This Issue Experts Recommend Steps to Increase Colorectal Cancer Screening in Primary Care »  Profiles in Cancer Research: Dr. Raju Kucherlapati »  Cancer Center Profile: The University of Texas M. D. Anderson Cancer Center »  Featured Clinical Trial: Optimizing Chemotherapy with Bevacizumab for Ovarian Cancer »  Operation Cessation: Curbing Military and Veteran Tobacco Use »  Updates Read This Issue FDA Update »  NIH Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for January 26, 2010

January 26, 2010 • Volume 7 / Number 2 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue St. Jude, Washington University Launch Genome Project for Childhood Cancers »  Adjuvant Chemotherapy May Benefit Older Patients with Colorectal Cancer »  Brain Cancer, Like Other Cancers, Has Distinct Subtypes »  Strategy May Enhance Umbilical Cord Blood Transplants »  Acupuncture Reduces Joint Pain in Some Women with Breast Cancer »  Genome Scans for Pancreatic Cancer Yield Clues to Risk »  Commentary Read This Issue Guest Director's Update: Major Grant Application Changes Now in Effect » A Conversation about Sequencing Cancer Genomes with Dr. Elaine Mardis » In Depth Read This Issue Trials Point to Potential Advances in Lung Cancer Treatment »  Helping Breast Cancer Gene Mutation Carriers Weigh Prevention Choices »  The Downside of Diagnostic Imaging »  Featured Clinical Trial: Adjuvant Bevacizumab and Chemotherapy for High-risk Breast Cancer »  Chinese and American Scientists Meet to Discuss Environmental Causes of Cancer »  Updates Read This Issue Cancer.gov Update »  Notes »

NCI Cancer Bulletin for January 12, 2010

January 12, 2010 • Volume 7 / Number 1 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Physicians Urged to Consider Active Surveillance in Prostate Cancer »  Study Weighs Comparative Effectiveness of Low-risk Prostate Cancer Treatments »  Lenalidomide Helps Delay Progression of Multiple Myeloma »  Genetic Study of Lymphoma Tumors Points to Possible Therapies »  Vaccine Kills Residual Leukemia Cells in Patients Treated with Imatinib »  Cancer Cells Use Stored Fats to Fuel Aggressive Growth and Spread »  Commentary Read This Issue Guest Director's Update: Targeting Barriers, including Insurance Coverage, to Improve Clinical Trial Participation » Guest Commentary by Brenda Nevidjon: Health Care Changes—How Cancer Care Initiatives Can Help » In Depth Read This Issue Ovarian Cancer Study Tests Lead Time of Potential Biomarkers »  New Cancer Drugs Bring New Side Effects, and Nurses Respond »  Video Eases End-of-Life Care Discussions »  Featured Clinical Trial: PARP Inhibitor and Metronomic Chemotherapy for Refractory Cancer »  Updates Read This Issue CDC Update »  Notes »