NCI Cancer Bulletin for June 28, 2011

June 28, 2011 • Volume 8 / Number 13 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: New Graphic Tobacco Warning Labels Backed by Research »  Common Gene Mutation Found in Hairy Cell Leukemia »  New Cancer Vaccine Shows Promise against Tumors in Mice »  Researchers Scrutinize Genetic Variants Linked to Melanoma »  Barrett Esophagus May Progress to Cancer Less Often than Thought »  Commentary Read This Issue A Conversation with Dr. Martha Linet on Cell Phone Use and Cancer Risk » In Depth Read This Issue Imaging Boot Camp for Cancer Researchers »  Featured Clinical Trial: Adding Targeted Therapy to Treatment for Esophageal Cancer »  Updates Read This Issue FDA Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for June 14, 2011

June 14, 2011 • Volume 8 / Number 12 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: New Therapies Offer Much-Needed Options for Patients with Melanoma »  Ovarian Cancer Screening Method Fails to Reduce Deaths from the Disease »  Longer Imatinib Treatment for GIST Improves Survival »  High-Dose Methotrexate Extends Event-Free Survival for Children with Leukemia »  Combining Chemotherapy with Bevacizumab Improves Outcomes for Ovarian Cancer Patients »  Experimental Drug Shrinks Tumors in Rare Sarcoma »  International Study Tests Additional Radiation Therapy for Breast Cancer »  Patient Navigation Leads to Fewer Missed Oncology Appointments »  In Depth Read This Issue Exemestane Substantially Reduces Breast Cancer Risk »  Perfect Match: Unraveling the Origin of XMRV »  Featured Clinical Trial: Combining Second-Line Targeted Therapies for Advanced Kidney Cancer »  Cancer Advocates at ASCO: Connecting for a Cause »  Updates Read This Issue FDA Update »  Notes »

NCI Cancer Bulletin for May 31, 2011

May 31, 2011 • Volume 8 / Number 11 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Study Questions Benefit of Surgery versus Watchful Waiting in Some with Prostate Cancer »  Cabozantinib Shrinks Tumors and Bone Metastases in Prostate and Other Cancers »  Also in the Journals: Cabozantinib May Shrink Some Rare Thyroid Tumors »  End-of-Life Care for Lung Cancer Patients Differs in U.S. and Ontario »  Researchers Identify New Way Tumor Cells May Adapt to Stressful Conditions »  In Depth Read This Issue HPV and Pap Co-Testing Safely Extend Cervical Cancer Screening Intervals »  Despite Skepticism, HPV Vaccine Proves Effective »  Featured Clinical Trial: Metformin to Treat Early-Stage Breast Cancer »  Scientific Meetings through the Lens of Twitter »  Updates Read This Issue FDA Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for May 17, 2011

May 17, 2011 • Volume 8 / Number 10 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Chemotherapy Regimen Extends Survival in Advanced Pancreatic Cancer Patients »  Study Finds Colonoscopy Screening Overused in Medicare Beneficiaries »  Prostate Cancer Study Provides More Data on Surgery versus Watchful Waiting »  Breast Cancers Arising between Mammograms Have Aggressive Features »  Patient Reports of Family Cancer History Are Often Inaccurate »  In Depth Read This Issue In Rare Skin Cancer, Virus Emerges as Target and Tool »  Straight from the Source: Electronic Patient-Reported Outcomes »  Combining Targeted Cancer Therapies: Much Promise, Many Hurdles »  Featured Clinical Trial: Lenalidomide and Radiation for Children with Brain Cancers »  Updates Read This Issue FDA Update »  Legislative Update »  Notes »

NCI Cancer Bulletin for May 3, 2011

May 3, 2011 • Volume 8 / Number 9 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: FDA Approves Abiraterone for Advanced Prostate Cancer »  Tool Weighs Benefits, Risks of Raloxifene or Tamoxifen to Prevent Breast Cancer »  Intensity-Modulated Radiation Therapy Use for Breast Cancer Influenced by Reimbursement »  Whole-Genome Sequencing Improves Cancer Diagnoses »  Researchers Identify Proteins that Help Hepatitis C Virus Enter Liver Cells »  Commentary Read This Issue A Conversation with Drs. Maureen Hatch and Kiyohiko Mabuchi on the 25th Anniversary of the Chernobyl Nuclear Disaster »  In Depth Read This Issue Chernobyl Tissue Bank Provides a Unique Resource to Researchers »  Use and Acceptance of HPV Vaccine Still a Work in Progress »  Design Dilemma: The Debate over Using Placebos in Cancer Clinical Trials »  Featured Clinical Trial: Testing Dose-Dense Paclitaxel for Ovarian and Related Cancers »  Updates Read This Issue FDA Update »  Legislative Update »  Notes »

NCI Cancer Bulletin for April 19, 2011

April 19, 2011 • Volume 8 / Number 8 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Active Surveillance May Be Preferred Option in Some Men with Prostate Cancer »  Cancer Burden among People Infected with HIV Changing in U.S. »  Genetic Study Yields New Clues to Melanoma »  Signaling Molecule Selectively Kills Breast Cancer Cells »  Commentary Read This Issue Inside NCI: A Conversation with Dr. Lauren Wood »  In Depth Read This Issue Investigating Nature's Mysteries for Drug Development »  Debunking Cancer Myths, One Phone Call at a Time »  Featured Clinical Trial: Cediranib to Treat Alveolar Soft Part Sarcoma »  Updates Read This Issue FDA Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for April 5, 2011

April 5, 2011 • Volume 8 / Number 7 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Crossing Disciplines to Explore Questions about Cancer »  Latest Surveillance Data Show Cancer Cases and Deaths Continue to Decline »  Patients Taking Imatinib for CML Have Similar Risk of Death as General Population »  Risk of Second Cancer Following Radiation Therapy Is Small »  Immunotherapy Targets Pancreatic Tumors from the Outside »  Breast Cancer Genomes Sequenced to Study Drug Response »  Combination of Two Targeted Cancer Drugs Appears Safe in Early Testing »  Test May Detect Mesothelioma at the Earliest Stages »  In Depth Read This Issue Menopausal Estrogen Therapy Benefits and Risks Vary by Age, WHI Analysis Suggests »  For People with Rare Skin Cancer Syndrome, Drug Brings Relief and Hope »  Genome Study of Multiple Myeloma Opens New Avenues for Research »  Featured Clinical Trial: Inhibiting Tumor Angiogenesis in Metastatic Hormone-Refractory Prostate Cancer »  Updates Read This Issue FDA Update »  CMS Update »  Legislative Update »  Notes »

NCI Cancer Bulletin for March 22, 2011

March 22, 2011 • Volume 8 / Number 6 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Fertility Still Possible for Many Male Cancer Survivors, Study Finds »  U.S. Cancer Survivors Increase to Nearly 12 Million »  Thyroid Cancer Risk Persists in People Exposed to I-131 Radiation as Children »  Incidence Rate of Second Cancer in the Opposite Breast Has Declined in U.S. »  Eribulin Improves Survival of Women with Metastatic Breast Cancer »  Experimental Strategy May Overcome Resistance to Breast Cancer Drug »  Commentary Read This Issue Devastation and Hope: An NCI Scientist's First-Hand Account of Japan's Resilience »  In Depth Read This Issue Colorectal Cancer Test Targets Cancer Stem Cells in Blood »  Miniaturized Device Puts Nanotechnology to Work in Diagnosing Cancer »  Featured Clinical Trial: Novel Combination Chemotherapy for Localized Ewing Sarcoma »  Updates Read This Issue FDA Update »  Notes »

NCI Cancer Bulletin for March 8, 2011

March 8, 2011 • Volume 8 / Number 5 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Ovarian Cancer Study Raises Questions about Developing Markers for Early Detection »  Surgical Biopsy Is Overused for Evaluating Suspicious Breast Imaging Findings »  Adding Radiation to Chemotherapy Improves Outcomes in Early-Stage Hodgkin Lymphoma »  Trastuzumab after Chemotherapy Is Effective in HER2-Positive Breast Cancer »  Denosumab Reduces Risk of Bone Side Effects in Advanced Prostate Cancer »  High Rates of Human Papillomavirus Infection Found in Men »  Commentary Read This Issue Reenergizing the Agenda for Cancer Communication »  In Depth Read This Issue PSA Velocity Does Not Improve Prostate Cancer Detection »  The Epithelial-Mesenchymal Transition in Cancer: A Potentially Fatal Transformation? »  Featured Clinical Trial: Optimizing Adjuvant Therapy for Resected Pancreatic Cancer »  Radically Reducing Radiation Exposure during Routine Medical Imaging »  Updates Read This Issue Legislative Update »  Notes »

NCI Cancer Bulletin - February 22, 2011

February 22, 2011 • Volume 8 / Number 4 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Some Women May Not Need More Extensive Lymph Node Surgery for Breast Cancer »  Dutasteride May Slow Growth of Early-Stage Prostate Cancer »  Bisphosphonate Use May Reduce Colorectal Cancer Risk »  Common Genetic Deletion Found in Brain Cancers »  More DNA Rearrangements Found in Prostate Cancers »  Certain Physicians Are More Likely to Refer Patients to Clinical Trials »  In Depth Read This Issue Targeted Therapies May Be Effective Against Rare Pancreatic Cancer »  Profiles in Cancer Research: Dr. Robin Yabroff »  Featured Clinical Trial: Treating Multiply Relapsed or Refractory Hairy Cell Leukemia »  Updates Read This Issue HHS Update »  FDA Update »  Cancer.gov Update »  Notes »

NCI Cancer Bulletin for February 8, 2011

February 8, 2011 • Volume 8 / Number 3 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: When Combined with Chemo, Bevacizumab Is Associated with Increased Risk of Death »  Starting Hormone Therapy at Menopause Increases Breast Cancer Risk »  Vaccine Reduces HPV Infections in Young Men »  Adoptive Cell Transfer Targets New Cancer Antigen for Immunotherapy »  Mouse Studies Point to Prognostic Test for Prostate Cancer »  Protein May Help Predict Cancer Recurrence and Metastasis »  In Depth Read This Issue Coming Home to Roost: The Self-Seeding Hypothesis of Tumor Growth »  Featured Clinical Trial: Study of a Statin to Prevent Polyps after Colon Cancer Resection »  Translating Clinical Care for Callers to NCI's Cancer Information Service »  Updates Read This Issue FDA Update »  Notes »

NCI Cancer Bulletin for January 25, 2011

January 25, 2011 • Volume 8 / Number 2 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Genetic Study Reveals Clues to Pancreatic Neuroendocrine Tumors »  Trial Suggests New Treatment Option for Gastrointestinal Stromal Tumors »  Gene Test for Risk of Colorectal Cancer Recurrence Validated »  Newly Discovered Mutations May Help Drive Common Kidney Cancer »  Interferon-gamma Promotes UV-Induced Melanoma in a Mouse Model »  Commentary Read This Issue A Conversation with Dr. Angela Mariotto and Dr. Martin Brown on the Rising Costs of Cancer Care » In Depth Read This Issue Can Aspirin Reduce Cancer Risk and Mortality? »  Seeking Better Treatments for Brain Tumors in Children »  Featured Clinical Trial: Dose-Adjusted Chemotherapy for Untreated c-MYC-Positive Lymphomas »  NCI Director Provides Update on New Programs and Initiatives »  Updates Read This Issue FDA Update »  Notes »

NCI Cancer Bulletin for January 11, 2011

January 11, 2011 • Volume 8 / Number 1 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue Featured Article: Continued Shortage of Chemotherapy Drugs Causing Concern »  Another JAK2 Inhibitor Shows Promise against Myelofibrosis »  Treatment for Ductal Carcinoma In Situ Varies Substantially »  Major Gene Mutation Identified in Lymphoma Tumors »  Commentary Read This Issue Inside NCI: A Conversation with Dr. Barry Kramer about Cancer Screening » In Depth Read This Issue Preserving Fertility While Battling Cancer »  Featured Clinical Trial: Comparing First-Line Therapies for Mucinous Ovarian or Fallopian Tube Cancer »  The Kimmel Cancer Center at Thomas Jefferson University »  Updates Read This Issue Notes »

Seasons Greetings

December 28, 2010 Dear NCI Cancer Bulletin Subscriber, The editors, writers, and technical staff of the NCI Cancer Bulletin would like to wish each of you a safe and joyous holiday season and a happy and healthy new year. Next month, we will begin our eighth year of publication. Since launching in 2004, we have published nearly 250 issues and well over 3,500 cancer research news stories, all of which can be accessed through our archive/search page. Last year in particular brought a host of important news and feature stories. Many of these are included in our "2010 Editors' Picks" list. We chose these stories not only for their potential impact on clinical practice, but also for their value as important but underreported topics. Finally, here is a sneak peek at our 2010 reader satisfaction survey results, which will also be posted in our first issue of 2011. Thanks to all who participated and sent in suggestions and comments. The overall results mirror our 2007 survey and, while there are obvious limitations with any voluntary survey, we believe the data and suggestions will help inform our future plans for the newsletter as we strive to meet reader needs and expectations. Thank you again for your interest and support in 2010. We hope you'll continue to read each issue and encourage others to subscribe. Best regards, The NCI Cancer Bulletin Team

NCI Cancer Bulletin for December 14, 2010

December 14, 2010 • Volume 7 / Number 24 Read the NCI Cancer Bulletin The latest issue of the NCI Cancer Bulletin is now available at http://www.cancer.gov/ncicancerbulletin. Keep up to date on the latest research and advances in the prevention, treatment, and understanding of cancer. News Read This Issue New Surgeon General's Report Outlines How Tobacco Smoke Causes Disease »  Study Estimates More than 600,000 Deaths Worldwide Caused by Secondhand Smoke »  Zoledronic Acid Does Not Improve Disease-Free Survival in Breast Cancer »  Regular Sunscreen Use May Reduce Invasive Melanoma Risk »  Hormone Therapy for Low-Risk Prostate Cancer Declines When Medicare Reimbursements Are Reduced »  Study Shows Strong Link between Obesity and Mortality »  New Subtype of Acute Myeloid Leukemia Identified »  Screening Compliance, Stage of Cancers Detected Vary by Demographic »  Commentary Read This Issue A Conversation with Dr. James Doroshow about NCI's Clinical Trials Cooperative Group Program » In Depth Read This Issue Trial Suggests New Treatment Option for Hodgkin Lymphoma »  Featured Clinical Trial: Targeting Tumor Metabolism in Papillary Kidney Cancers »  Statistical Strength in Numbers: International Clinical Trials for Rare Cancers »  Updates Read This Issue FDA Update »  Cancer.gov Update »  Notes »